Healing of root perforations treated with Mineral Trioxide Aggregate (MTA) and Portland cement

fourteen root perforations were performed for microscopic evaluation of the repair of interradicular tissue in dogs' teeth. these perforations were accomplished at low-speed with a stp 58 bur at the cervical third of the mesial root toward the furcation under irrigation with saline solution, followed by immediate sealing with proroot mta, mta-angelus and white portland cement. the dogs were killed after 90 days, revealing good results. the kruskal-wallis test did not demonstrate any statistically significant difference. it was concluded that the three materials showed good sealing in mineralized tissue, with complete closure, and they were free of inflammation in most teeth.