Adenocarcinomas mínimos de próstata en la biopsia sometidos a prostatectomía radical

fundamentals: valuation about clinical pathologyc facts of patients having undergone a radical prostatectomy due to a minimal prostate adenocarcinoma shown at the biopsy. methods: retrospective analysis of patients having undergone a radical prostatectomy due to a minimal prostate adenocarcinoma shown at the biopsy in front of the remaining radical prostatectomies. results: in 20 patients (7,6%) out of the 260 having undergone a radical prostatectomy between 1992 and 2004 the biopsy was informed as "minimal adenocarcinoma". these patients ranged 58 to 73 years with psa levels from 5.2 to 17.1 ng./ml. everyone except one were clinically t1c. at the definitive pathological study the gleason was 6, 4, 3 and 2 in 3, 3, 8 and 4 patients respectively, with one having a minimal adenocarcinoma not graded and another one with a pin ?. 3 showed only 1 focus with a tumoral volume less than 5% of the tissue (84.2% with significant tumor or multifocal). the final staging was 1 pt0 (pin ?), 7 pt2a, 11 pt2b and 1 pt3a (62.5% bilaterals). relating to the remaining patients under prostatectomy, patients with minimal adenocarcinoma presented significative differences in gleason sum (p < 0.029) and staging (p = 0.02); no in psa mean (p =0,243). summary: minimal adenocarcinomas of the prostate at the biopsy are significant but do present lower staging and grading in relation with the rest of patients.