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Amiloidosis vesical secundaria y hematuria masiva

DOI: 10.4321/S0210-48062010000100019

Keywords: secondary amyloidosis, urinary bladder, massive hematuria.

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Abstract:

objective: to report four additional cases of secondary amyloidosis of the bladder, an extremely rare condition, as shown by the cases reported in the literature. materials and methods: four clinical cases are reported, all of them occurring as hematuria, which was massive and fulminant and resulted in death in three patients. results: secondary amyloidosis of the bladder is of the aa type, which is more common in females and mainly secondary to rheumatoid arthritis, but also to ankylosing spondylitis and long-standing chronic inflammatory conditions. hematuria is the main and virtually only symptom. a pathological and immunohistochemical study confirmed diagnosis. all three patients who experienced massiva, fatal hematuria had an intercurrent condition requiring urethral catheterization, which was the triggering factor. conclusions: despite its rarity, as shown by the few cases reported, secondary amyloidosis of the bladder should be considered in patients already diagnosed with systemic amylodosis and/or the conditions reported who require simple urethral catheterization.

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