Early infantile form of galactosialidosis in a female baby with a prenatal diagnosis of fetal ascites: First case in Brazil

we present the first case of an early infantile form of galactosialidosis among brazilians. this very rare and severe lysosomal storage disease has only a dozen patients clearly diagnosed worldwide. clinical, pathological and biochemical features were consistent with previously published findings. we detected the disorder in a 7-month-old female baby with prenatal diagnosis of ascites. evolution of the storage disease was monitored through routine thin-layer chromatography (tlc) for urinary oligosaccharides as part of a screening program for inborn errors of metabolism (iem) in high-risk children, carried out in rio de janeiro.