Sarcoma indiferenciado primário no sistema nervoso central

introduction: the central nervous system (cns) sarcoma is a rare neoplasm with an incidence of 0.1% to 4.3% in intracranial tumors. they are aggressive with poor prognosis, and mostly treated with radical resection. report: 29 year-old male patient with episodes of seizures and diagnosed with intraparenchymal hemorrhage. during the surgery a well-defined lesion was identified. histology showed a spindle cell neoplasm with atypia and numerous mitoses. the immunohistochemical markers were positive only for vimentin and s-100. the diagnosis was high-grade undifferentiated sarcoma. conclusion: metastatic lesions and gliosarcoma should be excluded in the differential diagnosis of cns sarcomas.