Trastorno del crecimiento en el ni？o y adolescente con diabetes mellitus tipo 1

the effect of type 1 diabetes mellitus on the growth and development of children and adolescents remains controversial. some groups of investigators have reported that diabetes during the pediatric age will alter the growth of children, independently of the degree of metabolic control, while others, including our group, have demonstrated, that what is called a ？poor metabolic？ control, with chronic hyperglycemia reflected by elevated hba1c, will produce a decrease in growth velocity that will end in subjects with short stature for their genetic potential. the aim of this study is to analyze the effect that diabetes has on the physiopathology of growth factors and the role they play on the clinical and auxiological abnormalities that are seen in children with type 1 diabetes mellitus.