Estatinas en la insuficiencia cardiaca

since their discovery 30 years ago, statins have played an important role in the treatment and prevention of cardiovascular diseases based on their lipid lowering properties. given their pleiotropic activity, their clinical utility in the treatment of several diseases has been discussed. lately, based on multiple theories, evidence has emerged regarding the efficacy of these drugs in heart failure patients. a review is presented of the physiopathological basis supporting their use and of clinical evidence in favor and against it.