Síndrome de anticuerpos antifosfolípidos asociado a la presencia de inhibidor adquirido del factor IX en una paciente sin hemofilia

we report the case of a 23-year-old female patient with an antiphospholipid syndrome characterized by recurrent deep venous thromboses and fetal losses, with positive lupus anticoagulant and anticardiolipin antibodies. during the course of the disease she had hemorrhagic manifestations not attributable to oral anticoagulants. hematological analyses documented reduced levels of factors ix and viii, with evidence of a specific inhibitor of factor ix. the deficiency of clotting factors improved with steroids and cyclophosphamide. (acta med colomb 2011; 36: 196-199)