SISTEMA INMUNE Y VACUNACIóN DE PECES

the fish immune system posses many of the cells and molecules found in higher vertebrates, but several other components and functions such as the melano-macrophage centers and the phagocityc activity of the epithelial enteric cells which are not found in higher vertebrates are described in fish, though their function is poorly understood. in adition, the aquatic environment, and even most, the productive systems are very complex, so that, the possibilities of the biological interactions are enormous and the biological processes prediction, difficult. vaccination is perhaps one the most important tools for fish bacterial diseases control, no just for its preventive and corrective potential but also for its beneficial environmental and public health effects which contrast with those of the antibiotic therapy. a great deal of the success of a vaccine in piscine species depends on fish immune system understanding, on the host-environment-pathogen interactions, but also on the productive system particularities. despite all these considerations, the vaccination in aquatic systems must be approached bearing in mind an integral perspective, where epidemiological, clinical, pathological and microbiological, etc. tools should be taken into account and not only the pharmacological therapy view.