Hipercalcemia como efecto secundario de los quelantes de potasio

hypercalcaemia is a potential adverse effect of calcium-containing ion exchange resins, often used in the treatment and prevention of hyperkalaemia in chronic kidney disease (ckd). we describe a series of seven outpatients with moderate ckd (mean glomerular filtration rate estimated with the ckd-epi formula: 41.29±10.83ml/min/1.73m2), presenting mild hypercalcaemia in relation to the treatment with calcium polystyrene sulfonate. serum calcium increased a mean of 0.91±0.46mg/dl, with a mean concomitant decrease of serum intact parathormone (ipth) of 52.24±49.29ng/dl. after treatment withdrawal or dose reduction, we observed a recovery of serum calcium and ipth values. treatment with calcium-based potassium binders should be included in the differential diagnosis of hypercalcaemia in patients with moderate ckd.