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Marcadores clínicos y humorales relacionados con la mortalidad en pacientes con insuficiencia cardíaca clase funcional III/IV

Keywords: heart failure, clinical and humoral markers, systolic dysfunction.

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Abstract:

aim. to study the existence of clinical and humoral variables that behave as predictors of mortality risk in patients with dilated cardiomyopathy (dcm) and heart failure (hf) functional class iii/iv new york heart association. material and methods. we consecutively included 84 patients with dcm and hf over a year old of diagnosis (mean 3.3 years/sd 2.1), hospitalized at coronary care unit due to cardiac decompensation. patients were divided into two groups: not dead group (gv) n=60, and group of those who died (gm) n=24. at the end of the study we compared: rehospitalizations, comorbidities, hygienic-dietary treatment accomplishment, adherence to pharmacological treatment, pharmacological treatment at income (drugs), and biochemical variables: natremia, white blood cell count, glucose, creatinine in blood, bilirubinemia. results. every patient had cardiothoracic index >0.5 and moderate to severe impairment of ventricular function by echocardiogram among both groups. within sex distribution there was a masculine predominance (gv: 83.3% and gm: 70.8%; p=ns), age gv: 61.3±11.0 years old and gm: 63.9±11.3 (p=ns). conclusion. of all analyzed variables, were associated with worst prognosis: the largest number of readmissions, treatment with furosemide, leukocytosis (white blood cells > 11000 per mm3) and creatinine values > 2 mg/dl.

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