Analysis and Modeling of the Neonatal Mortality Rate by Fitting Probabilistic Distributions: Comparison of HLPKD, Weibull, Gamma, Lindley and Gompertz Models
This study compares five probabilistic distributions whose HLPKD, Weibull, Gamma, Gompertz and Lindley for modeling annual neonatal mortality rates in Burkina Faso over the period 1969-2023. The objective is to identify the most appropriate model for describing the distribution of this indicator and to evaluate estimator stability through simulation. Parameters were estimated using the maximum likelihood method based on data compiled by the United Nations Inter-agency Group for Child Mortality Estimation (UN IGME), accessible via the CEIC database. Monte Carlo simulations were conducted using R software (version 4.3.2) with
replications for sample sizes
. Performance criteria included bias, relative bias, mean squared error (MSE), root mean squared error (RMSE), average confidence interval lengths (AL90 and AL95) and coverage probabilities (CP90 and CP95). For the real data, goodness-of-fit was assessed using log-likelihood (lnL), Akaike information criterion (AIC), Bayesian information criterion (BIC), the Kolmogorov-Smirnov test (KS), mean absolute error (ASAE), the Cramér-von Mises test (
) and the Anderson-Darling test (
). Bootstrap-corrected p-values were also computed to account for parameter estimation uncertainty. The simulations showed that the Weibull, Gamma, Gompertz and Lindley models converge rapidly to stable estimates, whereas HLPKD requires larger sample sizes to achieve comparable precision. The application to real data identified the Gamma and HLPKD models as the best-fitting, with high p-values (0.8431 for Gamma and 0.9050 for HLPKD) and small discrepancies between theoretical distributions and observations. The Gamma model stands out for its parsimony (two parameters) and estimation stability, while HLPKD, despite its flexibility, suffers from greater uncertainty in its parameter
. Bootstrap-corrected tests confirmed that Gamma and HLPKD are the only models not rejected at the 5% level. The Gamma model emerges as the most reliable for describing the distribution of
References
[1]
Nakakana, U.N., Rouamba, T., Camara, B., Bognini, J.D., et al. (2025) Neonatal Mor tality in the Gambia and Burkina Faso: Insights to Incidence and Risk Factors from Clinical Trial Data. medRxiv https://doi.org/10.1101/2025.11.02.25339325
[2]
Gompertz, B. (1825) On the Nature of the Function Expressive of the Law of Human Mortality, and on a New Mode of Determining the Value of Life Contingencies. Philosophical Transactions of the Royal Society of London, 115, 513-583. https://doi.org/10.1098/rstl.1825.0026
[3]
Willemse, W.J. and Kaas, R. (2007) Rational Reconstruction of Frailty-Based Mortality Models by a Generalisation of Gompertz’ Law of Mortality. Insurance: Mathematics and Economics, 40, 468-484. https://doi.org/10.1016/j.insmatheco.2006.07.003
[4]
Yadav, S.K., Singh, S.K. and Kumar, A. (2025) Reliability Analysis of the Lindley Distribution via Unified Hybrid Censoring with Applications in Medical Survival and Biological Lifetime Data. Journal of Statistical Theory and Practice, 19, Article 45.
[5]
Alduais, F.S. and Khan, Z. (2025) Development of Neutrosophic Gamma Distribution for Modeling Neonatal Mortality Data. Neutrosophic Sets and Systems, 79, 48-62.
[6]
AlTwijri, M.I., Alshahrani, N.D., Elgarhy, M., Elsehetry, M. and Elkalzah, B. (2026) A New Three-Parameter Statistical Distribution with Applications to Biomedical and Radiation Data. Journal of Radiation Research and Applied Sciences, 19, Article 102167. https://doi.org/10.1016/j.jrras.2026.102167
[7]
Legesse, B.T., Abera, N.M., Alemu, T.G. and Atalell, K.A. (2023) Incidence and Predictors of Mortality among Neonates with Respiratory Distress Syndrome Admitted at West Oromia Referral Hospitals, Ethiopia, 2022. Multi-Centred Institution Based Retrospective Follow-Up Study. PLOS ONE, 18, e0289050. https://doi.org/10.1371/journal.pone.0289050
[8]
Daka, D.T., Wubneh, C.A., Alemu, T.G. and Terefe, B. (2023) Incidence and Predictors of Mortality among Neonates Admitted with Perinatal Asphyxia at West Oromia Tertiary Hospitals, Ethiopia, 2022. BMC Pediatrics, 23, Article No. 475. https://doi.org/10.1186/s12887-023-04313-6
[9]
Hussain, S., Ul Hassan, M., Rashid, M.S. and Ahmed, R. (2023) Families of Extended Exponentiated Generalized Distributions and Applications of Medical Data Using Burr III Extended Exponentiated Weibull Distribution. Mathematics, 11, Article 3090. https://doi.org/10.3390/math11143090
[10]
Johnson, N.L. and Kotz, S. (1970) Distributions in Statistics: Continuous Univariate Distributions, Vol. 1. Wiley.
[11]
Nedjar, S. (2017) Poisson Pseudo Lindley Distributions et leurs applications en assurance vie. Université Badji Mokhtar Annaba.
[12]
CEIC Data (2026) Burkina Faso BF: Mortality Rate: Neonatal: Per 1000 Live Births, 1969-2023. https://www.ceicdata.com/en/burkina-faso/social-health-statistics/bf-mortality-rate-neonatal-per-1000-live-births
[13]
Efron, B. and Tibshirani, R.J. (1993) An Introduction to the Bootstrap. Chapman and Hall/CRC.
[14]
Burton, A., Altman, D.G., Royston, P. and Holder, R.L. (2006) The Design of Simulation Studies in Medical Statistics. StatisticsinMedicine, 25, 4279-4292. https://doi.org/10.1002/sim.2673
[15]
R Core Team (2024) R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing.
[16]
Devroye, L. (1986) Non-Uniform Random Variate Generation. Springer.
[17]
Koehler, E., Brown, E. and Haneuse, S.J.P.A. (2009) On the Assessment of Monte Carlo Error in Simulation-Based Statistical Analyses. TheAmericanStatistician, 63, 155-162. https://doi.org/10.1198/tast.2009.0030