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Identification and Distribution of Pathogenic Bacteria Isolated from Suppurative Infections at Kindia Regional Hospital in Guinea

DOI: 10.4236/aim.2026.169024, PP. 424-437

Keywords: Pyogenic Infections, Bacterial Species, Distribution, Hospital Units, Republic of Guinea

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Abstract:

Background: Healthcare-associated infections, particularly suppurative wounds, represent a major cause of patient morbidity. This study aimed to identify the pathogenic bacteria isolated from suppurative infections and determine their distribution across units at Kindia Regional Hospital. Methods: We conducted a prospective, cross-sectional descriptive study from December 2022 to December 2025 at Kindia Regional Hospital. Standard microbiological methods were used to identify bacterial species from 4293 collected pus samples. Results: In our study, females constituted the majority (81.7%), and the [20 - 29 years] age group was the most represented (33.7%). Analysis of the patients’ occupations revealed that 49% of the participants were “housewives,” followed by “retail workers” at 19%. Staphylococcus aureus (22%) was the most prevalent species, followed by Escherichia coli (10%). In our study, bacteria such as Streptococcus agalactiae, and Streptococcus pyogenes were isolated exclusively from female patients. Conclusion: This study will help strengthen microbiological surveillance of suppurative infections and contribute to improved care for patients suffering from pyogenic infections.

References

[1]  Scalise, A., Bianchi, A., Tartaglione, C., Bolletta, E., Pierangeli, M., Torresetti, M., et al. (2015) Microenvironment and Microbiology of Skin Wounds: The Role of Bacterial Biofilms and Related Factors. Seminars in Vascular Surgery, 28, 151-159.
https://doi.org/10.1053/j.semvascsurg.2016.01.003
[2]  Dryden, M.S. (2010) Complicated Skin and Soft Tissue Infection. Journal of Antimicrobial Chemotherapy, 65, iii35-iii44.
https://doi.org/10.1093/jac/dkq302
[3]  Rameshkannan, S., Nileshraj, G., Rameshprabu, S., Mangaiarkkarasi, A. and Meher Ali, R. (2014) Pattern of Pathogens and Their Sensitivity Isolated from Pus Culture Reports in a Tertiary Care Hospital, Puducherry. Indian Journal of Basic and Applied Medical Research, 4, 243-248.
[4]  Freiberg, J.A. (2017) The Mythos of Laudable Pus along with an Explanation for Its Origin. Journal of Community Hospital Internal Medicine Perspectives, 7, 196-198.
https://doi.org/10.1080/20009666.2017.1343077
[5]  Kursheed, F., Tabassum, A., Farwa, U., Wazir, S., Shafiq, M. and Sheikh, A.K. (2024) The Antibiogram of Pus Cultures in Federal Tertiary Care Hospital, Islamabad and Its Utility in Antimicrobial Stewardship. Iranian Journal of Microbiology, 16, 56?61.
https://doi.org/10.18502/ijm.v16i1.14871
[6]  Misha, G., Chelkeba, L. and Melaku, T. (2021) Bacterial Profile and Antimicrobial Susceptibility Patterns of Isolates among Patients Diagnosed with Surgical Site Infection at a Tertiary Teaching Hospital in Ethiopia: A Prospective Cohort Study. Annals of Clinical Microbiology and Antimicrobials, 20, Article No. 33.
https://doi.org/10.1186/s12941-021-00440-z
[7]  N’goran, S.E.K., Yapi, I.A.D., Bahan, G.A.J., Gninissemet, A.J., N’guiachi, M.A.E., Angora, K.E., Tea, Z.B. and Kacou-n’douba, A. (2025) Profils microbiologiques des otorrhees au chu de cocody, c?te d’ivoire en 2019. Revue Bio-Africa, No. 32, 14-21.
https://bioafrica-ci.org/revues/N%C2%B033-2025/1763565564_2-ProfilsMicrobiologiques.pdf
[8]  Abdoulaye, O., Harouna Amadou, M.L., Amadou, O., Adakal, O., Lawanou, H.M., Boubou, L., et al. (2018) Aspects épidémiologiques et bactériologiques des infections du site opératoire (ISO) dans les services de chirurgie à l’H?pital National de Niamey (HNN). Pan African Medical Journal, 31, Article 33.
https://doi.org/10.11604/pamj.2018.31.33.15921
[9]  Ngaroua, Ngah, J.E., Bénet, T. and Djibrilla, Y. (2016) Incidence des infections du site opératoire en Afrique sub-saharienne: Revue systématique et méta-analyse. Pan African Medical Journal, 24, Article 171.
https://doi.org/10.11604/pamj.2016.24.171.9754
[10]  Wilson, J.W., Schurr, M.J., LeBlanc, C.L., Ramamurthy, R., Buchanan, K.L. and Nickerson, C.A. (2002) Mechanisms of Bacterial Pathogenicity. Postgraduate Medical Journal, 78, 216-224.
https://doi.org/10.1136/pmj.78.918.216
[11]  Bazibuhe, P.L., Murhula, A.C., Mbikilile, M.J., Bandeke, D., Rutega, J.F. and Alumeti Munyali, D. (2024) Les infections du site opératoire: Fréquence, bactériologie et l’antibiogramme à l’est de la République Démocratique du Congo. Kivu Medical Journal, 2, 1-10.
https://doi.org/10.64263/kmj.v2i2.38
[12]  Mwakalinga, L.K., Temu, R.J., Horumpende, P.G., Ngowi, N. and Pallangyo, A.J. (2022) Bacterial Isolates and Their Antibiotic Susceptibility Pattern among Patients with Infected Wounds Admited in Orthopaedic and Trauma Ward in Tertiary Care Hospital North-Eastern Tanzania. Journal of Biosciences and Medicines, 10, 83-96.
https://doi.org/10.4236/jbm.2022.107007
[13]  Bafeno Lyande, L., Basandja, E., Tagoto, A., Luka A, G., Lobwa Bosongo, S., Pami, L., et al. (2024) Analyse des facteurs associés aux infections du site opératoire à Kisangani (Expérience de l’h?pital général de référence Makiso-Kisangani). Journal Africain des Cas Cliniques et Revues, 6, 44-52.
https://doi.org/10.70065/24jinf64.002l063012
[14]  Suragul, W., Rungsakulkij, N., Vassanasiri, W., Tangtawee, P., Muangkaew, P., Mingphruedhi, S., et al. (2020) Predictors of Surgical Site Infection after Pancreaticoduodenectomy. BMC Gastroenterology, 20, Article No. 201.
https://doi.org/10.1186/s12876-020-01350-8
[15]  Berríos-Torres, S.I., Umscheid, C.A., Bratzler, D.W., Leas, B., Stone, E.C., Kelz, R.R., et al. (2017) Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017. JAMA Surgery, 152, 784-791.
https://doi.org/10.1001/jamasurg.2017.0904
[16]  Allegranzi, B., Nejad, S.B., Combescure, C., Graafmans, W., Attar, H., Donaldson, L., et al. (2011) Burden of Endemic Health-Care-Associated Infection in Developing Countries: Systematic Review and Meta-Analysis. The Lancet, 377, 228-241.
https://doi.org/10.1016/s0140-6736(10)61458-4
[17]  Mangram, A.J., Horan, T.C., Pearson, M.L., Silver, L.C. and Jarvis, W.R. (1999) Guideline for Prevention of Surgical Site Infection, 1999. Infection Control & Hospital Epidemiology, 20, 247-280.
https://doi.org/10.1086/501620
[18]  Owens, C.D. and Stoessel, K. (2008) Surgical Site Infections: Epidemiology, Microbiology and Prevention. Journal of Hospital Infection, 70, 3-10.
https://doi.org/10.1016/s0195-6701(08)60017-1
[19]  Subhani, M.M., Vamsi, S., Bhumireddy, R.R., Brungi, S. and Roopa, C. (2025) Bacteriological Profile and Antibiotic Sensitivity Patterns of Aerobic Organisms Isolated from Pus Samples: A Study Conducted in Tertiary Care Hospital, Mahabubnagar. Biomedicine, 45, 141-146.
[20]  Makgatho, M.E., Sethowa, J. and Mashinya, F. (2019) Bacterial Isolates and Antimicrobial Susceptibility Profiles in Wound Swabs from Central Polokwane NHLS, in Limpopo Province, South Africa. African Journal of Biomedical Research, 22, 229-233.
[21]  Guta, M., Aragaw, K. and Merid, Y. (2014) Bacteria from Infected Surgical Wounds and Their Antimicrobial Resistance in Hawassa University Referral Teaching Hospital, Southern Ethiopia. African Journal of Microbiology Research, 8, 1118-1124.
https://doi.org/10.5897/ajmr2013.6544
[22]  Tong, S.Y.C., Davis, J.S., Eichenberger, E., Holland, T.L. and Fowler, V.G. (2015) Staphylococcus Aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management. Clinical Microbiology Reviews, 28, 603-661.
https://doi.org/10.1128/cmr.00134-14
[23]  Mudassar, S., Khan, S.W., Ali, M. and Mahmood, F. (2018) Aerobic Bacteriological Profile and Antimicrobial Susceptibility Pattern of Pus Isolates in a Teaching Hospital, Lahore, Pakistan. International Journal of Contemporary Medical Research, 5, D1-D3.
https://doi.org/10.21276/ijcmr.2018.5.4.8
[24]  Sudhaharan, S., Kanne, P., Chavali, P. and Vemu, L. (2018) Aerobic Bacteriological Profile and Antimicrobial Susceptibility Pattern of Pus Isolates from Tertiary Care Hospital in India. The Journal of Infection in Developing Countries, 12, 842-848.
https://doi.org/10.3855/jidc.10473
[25]  Duff, P. (2026) Infection after Cesarean Delivery: Diagnosis, Pathophysiology, Management, and Prevention. American Journal of Obstetrics and Gynecology, 233, S464-S482.
https://doi.org/10.1016/j.ajog.2025.08.007
[26]  Dalton, E. and Castillo, E. (2014) Post Partum Infections: A Review for the Non-OBGYN. Obstetric Medicine, 7, 98-102.
https://doi.org/10.1177/1753495x14522784
[27]  Organisation Mondial de la Sante (2022) Global Report on Infection Prevention and Control.
https://www.who.int/publications/i/item/9789240051164
[28]  Magill, S.S., O’Leary, E., Janelle, S.J., Thompson, D.L., Dumyati, G., Nadle, J., et al. (2018) Changes in Prevalence of Health Care-Associated Infections in U.S. Hospitals. New England Journal of Medicine, 379, 1732-1744.
https://doi.org/10.1056/nejmoa1801550
[29]  Murray, P.R., Rosenthal, K.S. and Pfaller, M.A. (2021) Medical Microbiology. 9th Edition, Elsevier.
[30]  Raabe, V.N. and Shane, A.L. (2019) Group B Streptococcus (Streptococcus agalactiae). Microbiology Spectrum, 7, 1-13.
https://doi.org/10.1128/microbiolspec.gpp3-0007-2018
[31]  Bryant, A.E. and Stevens, D.L. (2020) Streptococcus Pyogenes. In: Bennett, J.E., Dolin, R. and Blaser, M.J., Eds., Mandell, Douglas, and Bennnett’s Principles and Practice of Infectious Diseases, Saunders, 2446-2461.

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