The Cyperus articulatus is a tall plant that grows mainly near the edges of rivers. One of its common names is priprioca. In this work was used priprioca native to the Amazon basin, where native tribes have used it as a medicine for hundreds of years. The essential oils from the rhizomes of Cyperus articulatus collected in Brazil were extracted by hydrodistillation and analyzed by two-dimensional chromatography with the objective of attaining very high-resolution second dimension separations. Recent studies on the chemical composition of essential oil by conventional have shown that this grass contains an amount of almost 50 constituents. The compound includes flavonoids, polyphenols, saponins, tannins, and terpenes. The main constituents of essential oil from Brazil were α-cyperone and cyperotundone. These latter two compounds are believed to be effective pain relievers, working in the same manner as aspirin and ibuprofen, and may also possess antimalarial properties. In this paper, the chemical composition of the essential oil of Cyperus articulatus was performed by Comprehensive Two-Dimensional Gas Chromatography coupled with Quadrupole Mass Spectrometric detection. This technique allowed the identification of about 100 constituents of the oil of Cyperus articulatus. Obviously, two-dimensional chromatography was better when compared to conventional chromatography.
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