Objectives: To evaluate the level of knowledge, source of information and level of acceptance in the use of dental implants among dental patients in replacement of missing tooth in two selected tertiary hospitals in South-West of Nigeria. Methodology: This was a descriptive cross-sectional study. A standardized, self-explanatory questionnaires were given to patients who presented at restorative clinics in the tertiary hospitals for the replacements of their missing teeth. Data were analyzed using frequencies and percentages for descriptive statistics. Binary logistic regression analysis was used to determine the factors associated with knowledge of dental implants; p < 0.05 was considered statistically significant for all the tests. Results: A total number of 201 participants were included in the study. More than half of participants had poor knowledge of tooth replacement methods and majority had poor knowledge of dental implants (80.6%). The majority of participants attained their information about dental implants from dentists (46.3%) as well as their knowledge of other prostheses (40.8%). Most (58.7%) considered dental implants as best treatment of choice. With increasing age, there were less odds of having good knowledge of dental implants (aOR = 0.963; CI = 0.932 - 0.994), Good knowledge of tooth replacement option increased the odds of having good knowledge of dental implants by 8 times (aOR = 7.858; CI = 3.011 - 20.510). Conclusion: There is lack of knowledge about dental implants in this part of the world and the majority had their source of information about implants from dentists. Most of the participants considered implants as the best treatment of choice and they are willing to know more about implants.
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