Introduction: Diabetes is a major cardiovascular risk factor, increasing the likelihood of developing ischemic heart disease. It is on the rise in Africa. Objective: We compared the socio-demographic, clinical and coronary angiography characteristics of diabetic patients with those of non-diabetic patients. Patients and methods: A case-control study over a three-years period from September 2019 to August 2022. All patients who underwent coronary angiography in the interventional cardiology unit of the teaching hospital “Mère-Enfant Le Luxembourg” of Bamako, Mali, were included. We compared patient coronary angiogram aspects of diabetic patients with non-diabetic patients. Results: We compiled 303 records of diabetic patients, which were compared with 507 records of non-diabetic patients. The mean age of diabetic patients was 61.20 ± 10.11 years, higher than that of non-diabetic patients (57.84 ± 12.88 years), with a statistically significant difference (p < 0.05). The male-to-female ratio was 1.56 for diabetic patients and 3.12 for non-diabetic patients. Hypertension was significantly more prevalent among diabetics (75.2%) compared to non-diabetics (55.2%) (p < 0.05). Smoking was significantly more prevalent among non-diabetics (31.6%) compared to diabetics (19.47%) (p < 0.05). Angina was more common among diabetics (37%) compared to non-diabetics (25.24%), with a significant difference (p < 0.05). Atypical chest pain was present in both groups, with no significant difference. Indication for coronary angiography in diabetic patients was ACS (37.6%). This indication was significantly more common in diabetic patients than in non-diabetic patients (p < 0.05). Three-vessel disease was more common in diabetic patients (34.32%) than in non-diabetic patients (18.50%), with a significant difference (p < 0.05). Conclusion: Coronary lesions are present in diabetic patients, with a predominance of three-vessel disease compared to non-diabetic patients.
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