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面向环境与安全检测的薄膜基荧光传感器研究进展
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Abstract:
近数十年来，用于爆炸物、非法药物、化学战剂与危险挥发性有机化学品检测的高性能薄膜荧光传感器研究获得了显著突破。一些FFS已经从实验室研究过渡到现实世界的应用，证明了它们的实际相关性。FFS技术的核心是传感膜，它在确定分析物和产生的信号方面起着至关重要的作用。薄膜基荧光传感器兼具灵敏度高、响应速度快、便于集成及适用于原位实时检测等优势，在环境监测、公共安全、食品药品安全及生物医学分析等领域展现出广阔的应用前景。本文针对其在不同应用场景下的研究进展进行了系统梳理与综述。最后，针对当前应用中存在的复杂基质干扰等问题进行了分析，并对智能化传感、柔性可穿戴器件及实用化检测装备的未来发展趋势进行了展望。
The development of high-performance thin-film fluorescence sensors (FFSs) for the detection of explosives, illicit drugs, chemical warfare agents, and hazardous volatile organic chemicals, among others, has made encouraging progress over the past few decades. Some FFS have transitioned from laboratory research to real-world applications, demonstrating their practical relevance. At the heart of FFS technology is the sensing membrane, which plays a crucial role in determining analytes and generated signals. Because of its high sensitivity, fast response speed, easy integration and suitability for in-situ real-time detection, thin film-based fluorescence sensors have shown wide application potential in environmental monitoring, public safety, food and drug safety and biomedical analysis. This paper systematically reviews its research progress in different application scenarios. Finally, the problems of complex matrix interference in current applications are analyzed, and the future development trend of intelligent sensing, flexible wearable devices and practical detection equipment is prospected.
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