By systematically examining the practical dilemmas confronting the traditional Industry-University-Research (IUR) collaboration model in terms of contractual mechanisms, achievement commercialization, and benefit distribution, this study focuses on the new IUR collaborative innovation paradigm constructed by the Immunology Frontier Research Center (IFReC) of Osaka University, which is driven by the concept of “co-creation”. Through a multi-dimensional analysis of IFReC’s groundbreaking practices in the initial collaboration stage, funding models, and contractual mechanisms, this study aims to extract its successful experience, explore its enlightenment for Chinese universities to deepen IUR collaboration, and provide a reference with both theoretical depth and practical value for promoting the innovation of the IUR collaboration paradigm.
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