Context: Factor V deficiency is a rare abnormality of coagulation as para-haemopilia, originally described by Owren in 1947, it is transmitted in an autosomal and recessive fashion. Its incidence is estimated at 1/10,000 in France. Clinical expressive is usually asymptomatic in the homozygous state. The diagnosis is based on a low prothrombin rate and normal TCK associated with a decrease in the factor of PFC in our context. Results: This was a 16-year-old male patient of normal build, born to consanguineous parents. He had sustained a head injury with the formation of an occipito-parietal hematoma. On admission, he was conscious, with moderate pallor of the skin and mucous membranes. The Complete Blood Count (CBC) showed normocytic anemia, a normal white blood cell and platelet count, PT at 59.5% and Activated Partial Thromboplastin Time (aPTT) Normal. Factor assays using a chronometric method revealed a factor V deficiency with normal factor VII. The patient received six transfusions of Fresh Frozen Plasma (FFP). The outcome was favorable, with progressive resorption and disappearance of the hematoma within a few days. Conclusion: Factor V deficiency is a very rare blood clotting disorder. It affects men and women equally and can, in some cases, cause significant bleeding.
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