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羰基脱氧官能团化反应研究进展
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Abstract:
醛、酮等羰基化合物在自然界中广泛存在，种类繁多，结构与功能各异，是廉价易得的化学化工原料。由于强C=O双键的同时裂解与转化具有很强的挑战性，通常需要特定的反应条件和试剂，且部分反应难以实现。近年来醛、酮脱氧领域迅速发展，脱氧官能团化方法日益进步。本文系统总结了醛、酮脱氧官能团化方法的发展和面临的挑战，为羰基脱氧官能团化的突破提供参考。
Carbonyl compounds such as aldehydes and ketones are widely present in nature, with a wide variety of types, diverse structures, and functions, and serve as inexpensive and readily available chemical and industrial raw materials. Due to the strong C=O double bond, simultaneous cleavage and transformation present significant challenges, usually requiring specific reaction conditions and reagents, and some reactions are difficult to achieve. In recent years, the field of aldehyde and ketone deoxygenation has developed rapidly, and methods for deoxygenation functionalization have been steadily improving. This article systematically summarizes the development and challenges of aldehyde and ketone deoxygenation functionalization methods, providing a reference for breakthroughs in carbonyl deoxygenation functionalization.
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