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Agricultural and Industrial Carcinogens as Cancer Resulting: Part II Consumption Goods

DOI: 10.4236/vp.2026.121005, PP. 48-71

Keywords: Agricultural Carcinogens, Industrial Carcinogens, Cancer Resulting Substances

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Abstract:

This paper is an integrative review and hypothesis paper based on observation and practical analytical experiments of Dr. Larysa Karaliova. The second part of a review series examines agricultural and industrial-consumption goods such as carcinogens and their contribution to cancer development. Part II focuses on consumer products, food-related exposures, and materials unsuitable for food contact that may contribute to carcinogenic risk. Particular attention is given to dietary, environmental, and industrial factors potentially involved in the development of colorectal (CRC)-, lung cancer addressing its multifactorial nature, including genetic susceptibility, metabolic status, lifestyle, and chronic exposure to exogenous carcinogens. The review analyzes agricultural, industrial, and consumer-product carcinogens, as well as endocrine-disrupting compounds and agents capable of suppressing immune function, as potential contributors to the increasing global incidence of malignant diseases. The analysis is based on peer-reviewed scientific literature, selected analytical experiments, documented real-world cases, and laboratory investigations conducted at the Norwegian Drug Control and Drug Discovery Institute. The relative importance and interaction of diet, environmental conditions, genetic predisposition, and chronic exposure to industrial and agricultural carcinogens are discussed. Comparative observations of cancer occurrence in selected animal species are also considered to support the evaluation of environmental carcinogenic risk.

References

[1]  Abegglen, L. M., Caulin, A. F., Chan, A., Lee, K., Robinson, R., Campbell, M. S. et al. (2015). Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans. JAMA, 314, 1850-1860.
https://doi.org/10.1001/jama.2015.13134
[2]  Brondz, I. (2025). To Remembrance Larysa Karaliova. Voice of the Publisher, 11, 1-3.
https://doi.org/10.4236/vp.2025.111001
[3]  Brondz, I., Karaliova, L., & Ekeberg, D. (2006). Biosensors as Electronic Compounds for Detectors in High-Performance Liquid Chromatography (HPLC). Electronic Components and Systems, 3, 25-27.
[4]  Choe, E., & Min, D. B. (2006). Mechanisms and Factors for Edible Oil Oxidation. Comprehensive Reviews in Food Science and Food Safety, 5, 169-186.
https://doi.org/10.1111/j.1541-4337.2006.00009.x
[5]  Chung, F. L., Chen, H. J., & Nath, R. G. (1996). Lipid Peroxidation as a Potential Endogenous Source for the Formation of Exocyclic DNA Adducts. Carcinogenesis, 17, 2105-2111.
[6]  de Visser, K. E., & Joyce, J. A. (2023). The Evolving Tumor Microenvironment: From Cancer Initiation to Metastatic Outgrowth. Cancer Cell, 41, 374-403.
https://doi.org/10.1016/j.ccell.2023.02.016
[7]  EFSA Panel on Contaminants in the Food Chain (CONTAM) (2017). Updated Scientific Opinion on Health Risks Arising from Chemical Mixtures. EFSA-Journal, 15, e04611.
[8]  Esterbauer, H., Schaur, R. J., & Zollner, H. (1991). Chemistry and Biochemistry of 4-Hydroxynonenal, Malonaldehyde and Related Aldehydes. Free Radical Biology and Medicine, 11, 81-128.
https://doi.org/10.1016/0891-5849(91)90192-6
[9]  Frankel, E. N. (1980). Lipid Oxidation. Progress in Lipid Research, 19, 1-22.
https://doi.org/10.1016/0163-7827(80)90006-5
[10]  Guéraud, F., Atalay, M., Bresgen, N., Cipak, A., Eckl, P. M., Huc, L. et al. (2010). Chemistry and Biochemistry of Lipid Peroxidation Products. Free Radical Research, 44, 1098-1124.
https://doi.org/10.3109/10715762.2010.498477
[11]  Guillén, M. D., & Cabo, N. (2002). Fourier Transform Infrared Spectra Data versus Peroxide and Anisidine Values to Determine Oxidative Stability of Edible Oils. Food Chemistry, 77, 503-510.
https://doi.org/10.1016/s0308-8146(01)00371-5
[12]  International Agency for Research on Cancer (IARC) (1995). Dry Cleaning, Some Chlorinated Solvents and Other Industrial Chemicals (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 63). IARC.
[13]  International Agency for Research on Cancer (IARC) (2000). Glycidol (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 77). IARC.
[14]  International Agency for Research on Cancer (IARC) (2007). Smokeless Tobacco and Some Tobacco-Specific N-Nitrosamines (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 89). IARC.
[15]  International Agency for Research on Cancer (IARC) (2010). Some Non-Heterocyclic Polycyclic Aromatic Hydrocarbons and Some Related Exposures (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 92). IARC.
[16]  International Agency for Research on Cancer (IARC) (2012a). A Review of Human Carcinogens: Personal Habits and Indoor Combustions (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 100E). IARC.
[17]  International Agency for Research on Cancer (IARC) (2012b). Chemical Agents and Related Occupations (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 100F). IARC.
[18]  International Agency for Research on Cancer (IARC) (2016). Perfluorooctanoic Acid, Tetrafluoroethylene, Dichloromethane, 1,2-Dichloropropane, and 1,3-Propane Sultone (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 110). IARC.
[19]  International Agency for Research on Cancer (IARC) (2018a). Agents Classified by the IARC Monographs, Volumes 1-123. IARC.
[20]  International Agency for Research on Cancer (IARC) (2018b). Benzene (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 120). IARC.
[21]  Karaliova, L. (2015). Ålesund—The Art Nouveau City. Voice of the Publisher, 1, 8-16.
https://doi.org/10.4236/vp.2015.11002
[22]  Karaliova, L., & Brondz, I. (2025). Agricultural and Industrial Carcinogens as Cancer Resulting: Part I. Voice of the Publisher, 11, 609-624.
https://doi.org/10.4236/vp.2025.114040
[23]  Kosmider, L., Cox, S., Zaciera, M., Kurek, J., Goniewicz, M. L., McRobbie, H. et al. (2020). Daily Exposure to Formaldehyde and Acetaldehyde and Potential Health Risk Associated with Use of High and Low Nicotine E-Liquid Concentrations. Scientific Reports, 10, Article No. 6546.
https://doi.org/10.1038/s41598-020-63292-1
[24]  Ludikhuyze, L., Rodrigo, L., & Hendrickx, M. (2000). The Activity of Myrosinase from Broccoli (Brassica oleracea L. Cv. Italica): Influence of Intrinsic and Extrinsic Factors. Journal of Food Protection, 63, 400-403.
https://doi.org/10.4315/0362-028x-63.3.400
[25]  Mishra, A., Chaturvedi, P., Datta, S., Sinukumar, S., Joshi, P., & Garg, A. (2015). Harmful Effects of Nicotine. Indian Journal of Medical and Paediatric Oncology, 36, 24-31.
https://doi.org/10.4103/0971-5851.151771
[26]  Nallasamy, P., Nimmakayala, R. K., Parte, S., Are, A. C., Batra, S. K., & Ponnusamy, M. P. (2022). Tumor Microenvironment Enriches the Stemness Features: The Architectural Event of Therapy Resistance and Metastasis. Molecular Cancer, 21, Article No. 225.
https://doi.org/10.1186/s12943-022-01682-x
[27]  Nitzkin, J. L., Farsalinos, K., & Siegel, M. (2015). More on Hidden Formaldehyde in E-Cigarette Aerosols. The New England Journal of Medicine, 372, 1575-1576.
[28]  Ogunwale, M. A., Li, M., Ramakrishnam Raju, M. V., Chen, Y., Nantz, M. H., Conklin, D. J. et al. (2017). Aldehyde Detection in Electronic Cigarette Aerosols. ACS Omega, 2, 1207-1214.
https://doi.org/10.1021/acsomega.6b00489
[29]  Powter, B., Jeffreys, S. A., Sareen, H., Cooper, A., Brungs, D., Po, J. et al. (2021). Human TERT Promoter Mutations as a Prognostic Biomarker in Glioma. Journal of Cancer Research and Clinical Oncology, 147, 1007-1017.
https://doi.org/10.1007/s00432-021-03536-3
[30]  Riaz, F., Zhang, J., & Pan, F. (2024). Forces at Play: Exploring Factors Affecting the Cancer Metastasis. Frontiers in Immunology, 15, Article 1274474.
https://doi.org/10.3389/fimmu.2024.1274474
[31]  Sanner, T., & Grimsrud, T. K. (2015). Nicotine: Carcinogenicity and Effects on Response to Cancer Treatment—A Review. Frontiers in Oncology, 5, Article 196.
https://doi.org/10.3389/fonc.2015.00196
[32]  Shen, Y., Chen, W., Fu, C., Liu, X., Miao, J., Li, J. et al. (2025). Polygenic Risk Score, Healthy Lifestyle Score, and Colorectal Cancer Risk: A Prospective Cohort Study. Cancer Epidemiology, Biomarkers & Prevention, 34, 290-297.
https://doi.org/10.1158/1055-9965.epi-24-1013

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