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糖尿病相关多种长期疾病流行趋势与死亡风险关联的研究综述
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Abstract:
糖尿病是一种以慢性高血糖为特征的代谢性疾病，患者常合并多种慢性疾病，即糖尿病相关长期疾病(Multiple Long-Term Conditions, MLTC)。此类疾病的流行趋势及其与死亡风险的关联已成为全球公共卫生的重要议题。目前研究表明，糖尿病MLTC患病率一直居高不下，以心血管疾病、慢性肾脏病及抑郁症等为主要构成，且部分MLTC呈显著上升趋势。然而，针对糖尿病MLTC流行趋势及其与死亡风险关联的系统性证据仍显不足。未来研究需依托大规模、长周期、具有全国代表性的队列数据，系统梳理糖尿病MLTC的流行趋势，并整合其与死亡风险的关联证据，从而为糖尿病MLTC的综合管理提供科学依据。
Diabetes is a metabolic disorder characterized by chronic hyperglycemia. Patients with diabetes often develop multiple chronic conditions, known as diabetes-related multiple long-term conditions (MLTC). The epidemiological trends of MLTC and their association with mortality risk have emerged as a critical global public health issue. Current evidence indicates that the prevalence of diabetes MLTC remains high, with cardiovascular disease, chronic kidney disease, and depression being common components, and some MLTCs showing a significant upward trend. However, there is still a lack of systematic evidence regarding the epidemiological trends of diabetes MLTC and its association with mortality risk. Future studies should utilize large-scale, long-term, nationally representative cohort data to systematically examine the trends of diabetes MLTC and integrate evidence on its association with mortality risk, thereby providing a scientific basis for the comprehensive management of diabetes MLTC.
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