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Atrial Fibrillation: Epidemiological, Clinical, Paraclinical, and Therapeutic Aspects in the Cardiology B Department of the Brazzaville University Hospital (Republic of Congo)

DOI: 10.4236/wjcd.2026.162014, PP. 137-146

Keywords: Atrial Fibrillation, Hypertension, Heart Failure, Congo

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Abstract:

Introduction: Atrial fibrillation (AF) is the most frequent cardiac arrhythmia encountered in clinical practice. The aim of this study was to assess the frequency of AF and to describe its epidemiological, clinical, paraclinical, and therapeutic characteristics in a Congolese hospital setting. Patients and Methods: This was a retrospective, descriptive study conducted in the Cardiology Department B of the Brazzaville University Hospital from January 1, 2022, to December 31, 2024. Medical records of patients hospitalized for atrial fibrillation were included. Results: Among 1550 patients admitted to the Cardiology B Department, 65 cases of AF were identified (4.2%). There were 41 women (63%). The mean age was 66.7 ± 15.4 years (range: 24 - 101 years). Past medical history included hypertension (61.5%), type 2 diabetes mellitus (12.3%), and ischemic stroke (6.1%). Dyspnea was present in 93.8% of cases. The mean heart rate was 101.5 ± 28.1 beats per minute. Clinical presentations included heart failure (81.5%) and left hemibody neurological deficit (9.2%). Electrocardiography revealed fine atrial fibrillation in 89.2% of cases. AF was permanent in 58.5%, persistent in 21.5%, and paroxysmal in 20%. Echocardiography showed left atrial enlargement in 36.9%, impaired left ventricular systolic function in 21.5%, reduced function in 20%, and preserved function in 4.6%. The predominant cardiac etiologies were hypertension (83%), including 61.5% as a cardiovascular risk factor and 21.5% as hypertensive heart disease, rheumatic valvular heart disease and dilated cardiomyopathy (27.7% each), and ischemic heart disease (6.1%). Treatment included digitalis (58.5%), beta-blockers (43.5%), and amiodarone (10.7%). Anticoagulant therapy was used in 75.4% of patients: vitamin K antagonists (58.5%) and direct oral anticoagulants (16.9%). In-hospital mortality occurred in six patients (9.2%). Conclusion: Atrial fibrillation remains frequent in the Congolese hospital setting and is mainly dominated by hemodynamic complications. Therapeutic management is essentially based on heart rate control and prevention of complications.

References

[1]  Rahman, F., Kwan, G.F. and Benjamin, E.J. (2014) Global Epidemiology of Atrial Fibrillation. Nature Reviews Cardiology, 11, 639-654.
https://doi.org/10.1038/nrcardio.2014.118
[2]  Hindricks, G., Potpara, T., Dagres, N., Arbelo, E., Bax, J.J., Blomström-Lundqvist, C., et al. (2020) 2020 ESC Guidelines for the Diagnosis and Management of Atrial Fibrillation Developed in Collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). European Heart Journal, 42, 373-498.
https://doi.org/10.1093/eurheartj/ehaa612
[3]  Traoré, B., Sidibé, S., Kantako, K., et al. (2021) Atrial Fibrillation at the Tombouctou Hospital: Frequency, Aetiologies, Treatment, and Outcome. Health Sciences and Disease, 22, 79-82.
[4]  Rakotonaivo, A., Raveloson, F.H.R., Ramiandrisoa, L.R. and Rabearivony, N. (2020) Epidemiological and Clinical Profile of Atrial Fibrillation in the Cardiology Department of CHU-JRB, Madagascar. JACCR Africa, 4, 171-176.
[5]  Mboup, W.N., Dia, K., Ka Mame, M., et al. (2024) Atrial Fibrillation at the Principal Hospital of Dakar, Senegal: Results and Limitations of Management. Annales de Cardiologie et d’Angéiologie, 73, Article ID: 101758.
[6]  Boombhi, J., Menanga, A., Mfeukeu-Kuaté, L., et al. (2019) Clinical and Therapeutic Characteristics of Atrial Fibrillation in a Hospital Setting in Yaoundé, Cameroon. Health Sciences and Disease, 20, 23-26.
[7]  Mboup, M.C., Kane, A., Jobe, M., Ndiaye, M.B., Bodian, M., Mbaye, A., et al. (2022) Prospective Evaluation of Hospitalized Patients with Atrial Fibrillation in Senegal. Postgraduate Medical Journal of Ghana, 4, 19-22.
https://doi.org/10.60014/pmjg.v4i1.80
[8]  Bouramoue, C., Kimbally-Kaky, G. and Ekoba, J. (2002) Adult Hypertension at the Brazzaville University Hospital: A Study of 4,928 Cases. Médecine d’Afrique noire, 49, 191-196.
[9]  Ellenga Mbolla, B.F., Gombet, T., Ikama, M.S., et al. (2006) Atrial Fibrillation: A Report of 131 Congolese Cases. Médecine d’Afrique noire, 53, 73-78.
[10]  Le Heuzey, J., Otmani, A., Marijon, E., Waintraub, X., Lepillier, A., Chachoua, K., et al. (2008) Fibrillation atriale: Le plus fréquent des troubles du rythme. La Presse Médicale, 37, 821-826.
https://doi.org/10.1016/j.lpm.2007.09.019
[11]  Camm, A.J., Kirchhof, P., Lip, G.Y.H., et al. (2010) ESC Guidelines for the Management of Atrial Fibrillation. European Heart Journal, 31, 2369-2429.
[12]  Lip, G.Y.H., Nieuwlaat, R., Pisters, R., Lane, D.A. and Crijns, H.J.G.M. (2010) Refining Clinical Risk Stratification for Predicting Stroke and Thromboembolism in Atrial Fibrillation Using a Novel Risk Factor-Based Approach. Chest, 137, 263-272.
https://doi.org/10.1378/chest.09-1584
[13]  Shoeb, M. and Fang, M.C. (2013) Assessing Bleeding Risk in Patients Taking Anticoagulants. Journal of Thrombosis and Thrombolysis, 35, 312-319.
https://doi.org/10.1007/s11239-013-0899-7
[14]  Mbaye, A., Pessinaba, S., Bodiane, M,. et al. (2010) Atrial Fibrillation: Frequency, Aetiological Factors, Outcome, and Treatment in a Cardiology Department in Dakar, Senegal. Pan African Medical Journal, 6, Article 16.
[15]  Longo-Mbenza, B., Kalonji, Y.A. and Milamba, J. (1993) Epidemiological and Electrocardiographic Aspects of Atrial Fibrillation in Black Adults in Congo. Information Cardiologique, 17, 227-232.
[16]  Ntep-Gweth, M., Zimmermann, M., Meiltz, A., Kingue, S., Ndobo, P., Urban, P., et al. (2010) Atrial Fibrillation in Africa: Clinical Characteristics, Prognosis, and Adherence to Guidelines in Cameroon. Europace, 12, 482-487.
https://doi.org/10.1093/europace/euq006
[17]  Wang, T.J., Larson, M.G., Levy, D., Vasan, R.S., Leip, E.P., Wolf, P.A., et al. (2003) Temporal Relations of Atrial Fibrillation and Congestive Heart Failure and Their Joint Influence on Mortality. Circulation, 107, 2920-2925.
https://doi.org/10.1161/01.cir.0000072767.89944.6e
[18]  Ragbaoui, Y., Chehbouni, C., Hammiri, A.E. and Habbal, R. (2017) Epidémiologie de l’association fibrillation atriale et insuffisance cardiaque. Pan African Medical Journal, 26, Article 116.
https://doi.org/10.11604/pamj.2017.26.116.11470
[19]  Coulibaly, S., Diall, I.B., Menta, I., et al. (2013) Atrial Fibrillation in the Cardiology Department of Point G University Hospital: Clinical Features, Aetiological Factors, and Natural Course. Tropical Cardiology, 25, 59-68.
[20]  Lévy, S., Maarek, M., Coumel, P., Guize, L., Lekieffre, J., Medvedowsky, J., et al. (1999) Characterization of Different Subsets of Atrial Fibrillation in General Practice in France: The ALFA Study. Circulation, 99, 3028-3035.
https://doi.org/10.1161/01.cir.99.23.3028
[21]  Sangaré, I., Bâ, H., Sagara, I., et al. (2022) Clinical and therapeutic aspects of atrial fibrillation in hospitalised patients at CHU Gabriel Touré. Health Sciences and Disease, 23.
[22]  Stambler, B. and Ngunga, L. (2015) Atrial Fibrillation in Sub-Saharan Africa: Epidemiology, Unmet Needs, and Treatment Options. International Journal of General Medicine, 8, 231-242.
https://doi.org/10.2147/ijgm.s84537
[23]  Kakkar, A.K., Mueller, I., Bassand, J.P., et al. (2017) Risk Profiles and Antithrombotic Treatment of Patients Newly Diagnosed with Atrial Fibrillation: Insights from the GAR-FIELD-AF Registry. American Heart Journal, 183, 1-9.
[24]  Nieuwlaat, R., Capucci, A., Camm, A.J., Olsson, S.B., Andresen, D., Davies, D.W., et al. (2005) Atrial Fibrillation Management: A Prospective Survey in ESC Member Countries. European Heart Journal, 26, 2422-2434.
https://doi.org/10.1093/eurheartj/ehi505

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