Background: Infection is a public health problem due to is high morbidity and mortality rate worldwide and his economic cost. Data on infection is available at the national level, but less known from the department of internal medicine of Bouaké University Hospital. The objective of our study was to determine the epidemiological aspects and mortality rates of infections in the Internal Medicine Department. Material and Methods: We conducted a cross-sectional analytical study over a period of six months, including all patients over the age of 15 with any type of infection. Results: Over a period of six months, 695 patients were hospitalized in the department and 211 of them had infection, representing a prevalence of 30.35%. The average age was 46.67 ± 18.41 years, with a sex ratio of 1.29. Bacterial infections were observed in 64.92% of cases, dominated by sepsis (14.69%). Parasitic infections (13.27%) were dominated by cerebral toxoplasmosis (7.58%) and malaria (5.68%), and viral infections (21.32%) were dominated by chronic viral hepatitis discovered at the complication stage (16.58%). There was no history of disease and/or comorbidities in 77.72% of cases. The outcome was favorable in 45.50% of cases and death was observed in 26.54% of cases. Mortality fell from 33.04% in the first quarter to 18.75% in the second quarter of the year, with a statistically significant difference. Conclusion: The prevalence of infections is high in the internal medicine department. They are dominated by sepsis and are responsible for high mortality with early death, particularly in the elderly.
References
[1]
Hutton, G., Chase, C., Kennedy-Walker, R. and Hamilton, H. (2024) Financial and Economic Costs of Healthcare-Associated Infections in Africa. Journal of Hospital Infection, 150, 1-8. https://doi.org/10.1016/j.jhin.2024.04.015
[2]
Boutayeb, A. (2010) The Impact of Infectious Diseases on the Development of Africa. In: Preedy, V.R. and Watson, R.R., Eds., Handbook of Disease Burdens and Quality of Life Measures, Springer, 1171-1188. https://doi.org/10.1007/978-0-387-78665-0_66
[3]
Murray, C.J.L., Ikuta, K.S., Sharara, F., Swetschinski, L., Robles Aguilar, G., Gray, A., et al. (2022) Global Burden of Bacterial Antimicrobial Resistance in 2019: A Systematic Analysis. The Lancet, 399, 629-655. https://doi.org/10.1016/s0140-6736(21)02724-0
[4]
Ge, Y., Liang, D., Cao, J., Gosling, R., Mushi, V. and Huang, J. (2023) How Socioeconomic Status Affected the Access to Health Facilities and Malaria Diagnosis in Children under Five Years: Findings from 19 Sub-Saharan African Countries. Infectious Diseases of Poverty, 12, 29-39. https://doi.org/10.1186/s40249-023-01075-2
[5]
Naghavi, M., Mestrovic, T., Gray, A., Gershberg Hayoon, A., Swetschinski, L.R., Robles Aguilar, G., et al. (2024) Global Burden Associated with 85 Pathogens in 2019: A Systematic Analysis for the Global Burden of Disease Study 2019. The Lancet Infectious Diseases, 24, 868-895. https://doi.org/10.1016/s1473-3099(24)00158-0
[6]
Ginaw, I.A. (2014) Hospital Acquired Infections among Patients Admitted in the Medical and Surgical Wards of a Non-Teaching Secondary Care Hospital in Northern India. Journal of Clinical and Diagnostic Research, 8, 81-83. https://doi.org/10.7860/jcdr/2014/6673.4014
[7]
Akoua-Koffi, C., Tia, H., Plo, J.K., Monemo, P., Cissé, A., Yao, C., et al. (2015) Epidemiology of Community-Onset Bloodstream Infections in Bouaké, Central Côte D’ivoire. New Microbes and New Infections, 7, 100-104. https://doi.org/10.1016/j.nmni.2015.06.009
[8]
Diop, M., Guitoula, C., Tamouh, A.G., Youbong, T., Daffé, S.M.M., Ndoye, M., et al. (2025) Prevalence of Bacterial Infections and Factors Associated with Death Related to These Infections in Two Medical Departments of a Tertiary Hospital in Dakar, Senegal. IJID Regions, 15, Article ID: 100623. https://doi.org/10.1016/j.ijregi.2025.100623
[9]
Farra, A., Mogalama, S., Diamant Mossoro-Kpinde, C., Ngaya, G., Robert Mbecko, J., Sanke-Waïgana, H., et al. (2022) Epidemiological Profile of Urinary Tract Infections Observed at the Institute Pasteur in Bangui, Central African Republic. American Journal of Biomedical and Life Sciences, 10, 36-41. https://doi.org/10.11648/j.ajbls.20221002.15
[10]
Simpore, A., Bazie, B.V.E.J.T., Yooda, P.A., Zoure, A.A., Sawadogo, S., Sawadogo, A., et al. (2024) Seroprevalence of Viral Hepatitis B and Occult Hepatitis B among Blood Donors in Africa: A Systematic Review and Meta-Analysis. Reviews in Medical Virology, 34, e70006. https://doi.org/10.1002/rmv.70006
[11]
Giefing-Kröll, C., Berger, P., Lepperdinger, G. and Grubeck-Loebenstein, B. (2015) How Sex and Age Affect Immune Responses, Susceptibility to Infections, and Response to Vaccination. Aging Cell, 14, 309-321. https://doi.org/10.1111/acel.12326
[12]
Ehounoud, B.C.H., Boumbanda Koyo, C.S., Doua Bongue, L., Cortaredona, S., N’Douba Kakou, A., Konan, D.B., et al. (2021) Assessment of the Burden of Malaria and Bacteraemia by Retrospective Molecular Diagnosis in Febrile Illnesses and First-Line Anti-Infectives in Côte D’ivoire. Travel Medicine and Infectious Disease, 43, Article ID: 102105. https://doi.org/10.1016/j.tmaid.2021.102105
[13]
Riches, N., Vinikoor, M., Guingane, A., Johannessen, A., Lemoine, M., Matthews, P., et al. (2023) Hepatitis B in Africa Collaborative Network: Cohort Profile and Analysis of Baseline Data. Epidemiology and Infection, 151, 1-10. https://doi.org/10.1017/s095026882300050x
[14]
Moyo, E., Mhango, M., Moyo, P., Dzinamarira, T., Chitungo, I. and Murewanhema, G. (2023) Emerging Infectious Disease Outbreaks in Sub-Saharan Africa: Learning from the Past and Present to Be Better Prepared for Future Outbreaks. Frontiers in Public Health, 11, Article ID: 1049986. https://doi.org/10.3389/fpubh.2023.1049986
[15]
Milleliri, J.M., Coulibaly, D. and Lamontagne, F. (2021) La Covid-19 en Côte d’Ivoire (mars 2020-avril 2021) une année sous le sceau du coronavirus. Médecine Tropicale et Santé Internationale, 1, 1-8.
[16]
Yapa, G.S.K., Kone, S., Kone, F., Kouame, K.G.R., Acho, J.K. and Ouattara, B. (2022) Maladies Auto-Immunes Systémiques dans les Services de Médecine Interne et de Dermatologie du Centre Hospitalier Universitaire de Bouaké: Profil de 50 patients. Revue Africaine de Médecine Interne, 9, 26-29.
[17]
Bauer, M., Gerlach, H., Vogelmann, T., Preissing, F., Stiefel, J. and Adam, D. (2020) Mortality in Sepsis and Septic Shock in Europe, North America and Australia between 2009 and 2019—Results from a Systematic Review and Meta-Analysis. Critical Care, 24, 239-243. https://doi.org/10.1186/s13054-020-02950-2