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药师参与1例术后呕吐致韦尼克脑病的药物治疗管理
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Abstract:
韦尼克脑病是一种急性综合征，需要紧急治疗以防止死亡和神经系统并发症。本文介绍了临床药师参与的一例胆囊癌根治术后并发韦尼克脑病的药物治疗管理，药师通过治疗浓度监测的手段在韦尼克脑病初期诊断，症状反复时鉴别原因方面发挥了较大作用。
Wernicke’s encephalopathy is an acute syndrome that requires urgent treatment to prevent death and neurological complications. This article introduces the medical treatment and management of a case of Wernicke’s encephalopathy after radical resection of gallbladder cancer in which clinical pharmacists participated. Pharmacists played a greater role in the early diagnosis of Wernicke’s encephalopathy and in identifying the cause when symptoms were repeated through therapeutic concentration monitoring.
| [1] | Ono, K., Hayano, S. and Kashima, M. (2023) Wernicke Encephalopathy: Limitations in a Laboratory and Radiological Diagnosis. BMJ Case Reports, 16, e254786. https://doi.org/10.1136/bcr-2023-254786 |
| [2] | Subramanian, S.M., Mendonca, T.M., K Srinivas, S. and Rodrigues, G.R. (2024) Sudden Vision Loss in Pregnancy: Wernicke’s Encephalopathy in a Patient with Hyperemesis Gravidarum. BMJ Case Reports, 17, e261085. https://doi.org/10.1136/bcr-2024-261085 |
| [3] | Kohnke, S. and Meek, C.L. (2020) Don’t Seek, Don’t Find: The Diagnostic Challenge of Wernicke’s Encephalopathy. Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 58, 38-46. https://doi.org/10.1177/0004563220939604 |
| [4] | Alexandri, M., Reynolds, B.Z., Smith, H., Golden, B.M., Gross, H. and Switzer, J.A. (2022) Wernicke’s Encephalopathy and Cranial Nerve VII Palsy in a 24-Year-Old Patient with COVID-19. International Journal of Emergency Medicine, 15, Article No. 6. https://doi.org/10.1186/s12245-022-00409-5 |
| [5] | Verma, R. and Kumar, C. (2020) Wernicke’s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation. Journal of Neurosciences in Rural Practice, 11, 487-488. https://doi.org/10.1055/s-0040-1713334 |
| [6] | Oudman, E., Wijnia, J.W., Oey, M., van Dam, M., Painter, R.C. and Postma, A. (2019) Wernicke’s Encephalopathy in Hyperemesis Gravidarum: A Systematic Review. European Journal of Obstetrics & Gynecology and Reproductive Biology, 236, 84-93. https://doi.org/10.1016/j.ejogrb.2019.03.006 |
| [7] | 李瑞雪, 刘晓涵, 曹文君, 等. 急性胆管炎合并韦尼克脑病1例报道[J]. 长治医学院学报, 2024, 38(2): 140-142. |
| [8] | Schabelman, E. and Kuo, D. (2012) Glucose before Thiamine for Wernicke Encephalopathy: A Literature Review. The Journal of Emergency Medicine, 42, 488-494. https://doi.org/10.1016/j.jemermed.2011.05.076 |
| [9] | Butterworth, R.F. (2003) Thiamin Deficiency and Brain Disorders. Nutrition Research Reviews, 16, 277-284. https://doi.org/10.1079/nrr200367 |
| [10] | 牟顺, 曾阳桥, 李晓琴, 等. 1例以言语不清为首发症状的非酒精性韦尼克脑病报告并文献复习[J]. 山东医药, 2024, 64(29): 52-55. |
