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A Novel Method for Identifying Pollen Allergens Using Chemically Modified Graphene

DOI: 10.4236/ampc.2026.162002, PP. 19-47

Keywords: Graphene Sensor, Chemical Modification, Pollen Allergen Detection, Graphene Doping, Four-Wire Method, Resistivity Measurement, Electrochemical Verification

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Abstract:

This study introduces a novel biosensor for detecting pollen allergens. The method involves chemically modifying a graphene surface with PBASE and specific IgG antibodies. The binding of target allergen proteins induces a doping effect, causing a measurable change in graphene’s electrical resistance, which allows for the identification and quantification of the allergens. The key finding is an exponential relationship between allergen concentration and the change in graphene’s resistivity.

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