Knowledge, Attitudes, and Practices of Healthcare Workers on Hepatitis B and C in Mbujimayi, Democratic Republic of the Congo: A Cross-Sectional Study

Introduction: Viral hepatitis B and C remain major public health concerns globally, particularly in Africa. In the Democratic Republic of the Congo (DRC), limited access to screening and treatment contributes to high morbidity and mortality. Healthcare professionals play a critical role in prevention and control efforts, yet their knowledge, attitudes, and practices (KAP) are not well documented in certain regions. Materials and Methods: We conducted a descriptive, cross-sectional study among healthcare professionals in two general referral hospitals in Mbujimayi, DRC, from July 1 to July 31, 2025. Data were collected using a structured electronic questionnaire via KoboCollect. KAP scores were assessed using predefined thresholds and analyzed using descriptive statistics, bivariate tests, and multivariate logistic regression to identify associated sociodemographic factors. Results: Among 191 participants, 90.05% demonstrated adequate knowledge, 93.72% had favorable attitudes, and 86.91% reported good practices. However, only 9.42% believed hepatitis B and C could be cured, and vaccination coverage was low (24.08%). Younger age (<35 years), lower education level, and non-physician roles (especially midwives and nurses) were significantly associated with lower KAP scores (p < 0.05). Fear of death and perceived high treatment costs were common concerns. Conclusion: While overall KAP levels were satisfactory, critical gaps persist in curability awareness and preventive practices, particularly among younger and non-physician staff. Targeted training and improved access to vaccination and treatment are essential to strengthening hepatitis control efforts in the region.