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Overview of Thyroid Disorders in Pikine National Hospital Center: A 10-Year Retrospective Study

DOI: 10.4236/ojemd.2025.1512024, PP. 279-288

Keywords: Thyroid Dysfunctions, Hyperthyroidism, Hypothyroidism, Thyroid Nodule, Goiter, Senegal

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Abstract:

Introduction: Thyroid diseases are common in our region. Their etiologies are diverse and can be classified into two major categories: functional disorders (hyperthyroidism and hypothyroidism) and structural abnormalities (nodules, goiter, and cancer). We conducted this study to assess the epidemiological and diagnostic profiles of thyroid diseases in our hospital. Methodology: This was a retrospective and descriptive study conducted over a 10-year period, from January 2009 to December 2019. A total of 920 patients diagnosed with thyroid disorders and followed at the Pikine National Hospital Center were included. Results: The mean age of the patients was 44 years, with ages ranging from 1 to 100 years. The highest incidence was observed in the 21 - 40-year age group. The female-to-male ratio was 7.7:1 (sex ratio, 0.13). Functional thyroid disorders were the most common indication for follow-up: hyperthyroidism accounted for 44.56% of cases, while hypothyroidism accounted for 35.87%. Among those with hyperthyroidism, thyrotoxic syndrome was present in 330 patients (81%), with Graves’ disease being the most frequent cause, responsible for 59% of hyperthyroidism cases. Hashimoto’s thyroiditis was the leading cause of hypothyroidism, found in 137 patients (41.51%), followed by post-thyroidectomy hypothyroidism, observed in 88 patients (26.66%). Structural thyroid diseases were mainly composed of thyroid nodules, followed by simple goiter and, less frequently, thyroid cancer. Conclusion: Thyroid disorders are frequent and have varied etiologies. Identifying the underlying cause is essential for effective management. Understanding the current epidemiological trends will facilitate future evaluations and healthcare planning.

References

[1]  Abodo, J., Yao, A., Koffi-Dago, P., et al. (2016) Characteristics of Thyroid Diseases in Côte d’Ivoire. Health Sciences and Disease, 20, 18-22.
[2]  Carlé, A., Bülow Pedersen, I., Knudsen, N., Perrild, H., Ovesen, L. and Laurberg, P. (2015) Gender Differences in Symptoms of Hypothyroidism: A Population-Based danthyr Study. Clinical Endocrinology, 83, 717-725.
https://doi.org/10.1111/cen.12787
[3]  Gueye, M. (2020) Therapeutic Management of Hyperthyroidism in Dakar in the Internal Medicine and Endocrinology-Diabetology Department of CHN Pikine: Retro-Spective Study of 430 Cases. Ph.D. Thesis, Cheikh Anta Diop University of Dakar.
[4]  Wemeau, J.L. (2010) Thyroid Diseases. Elsevier, 186 p.
[5]  Diagne, N., Faye, A., et al. (2016) Epidemiological, Clinical, Therapeutic, and Evolutive Aspects of Graves’ Disease in the Department of Internal Medicine at CHU Aristide Le Dantec, Dakar (Senegal). Pan African Medical Journal, 25, Article 6.
[6]  Diatou Gueye Dia, G., Hady Tall, T., et al. (2016) Epidemiological, Clinical, and Etiological Profile of Goiters in Saint Louis. Revue de Medecine Interne, 3, 41-43.
[7]  Ducarme, G., Bertherat, J., Vuillard, E., Polak, M., Guibourdenche, J. and Luton, D. (2007) Pathologies thyroïdiennes et grossesse. La Revue de Médecine Interne, 28, 314-321.
https://doi.org/10.1016/j.revmed.2007.01.011
[8]  Bartalena, L., Bogazzi, F., Chiovato, L., Hubalewska-Dydejczyk, A., Links, T.P. and Vanderpump, M. (2018) 2018 European Thyroid Association (ETA) Guidelines for the Management of Amiodarone-Associated Thyroid Dysfunction. European Thyroid Journal, 7, 55-66.
https://doi.org/10.1159/000486957
[9]  Dean, D.S. and Gharib, H. (2008) Epidemiology of Thyroid Nodules. Best Practice & Research Clinical Endocrinology & Metabolism, 22, 901-911.
https://doi.org/10.1016/j.beem.2008.09.019
[10]  Smith, T.J. and Hegedüs, L. (2016) Graves’ Disease. New England Journal of Medicine, 375, 1552-1565.
https://doi.org/10.1056/nejmra1510030
[11]  Dramé, B., Koné, A., Sow, D.S., Guindo, A., Maïga, I., Togo, A., et al. (2015) Aspects cliniques, biologiques et étiologiques de l’hypothyroïdie dans le service de médecine et d’endocrinologie de l’hôpital du Mali de Bamako. Annales d’Endocrinologie, 76, 418.
https://doi.org/10.1016/j.ando.2015.07.380
[12]  Fofana, S., et al. (2014) Clinical and Epidemiological Aspects of the Association of Diabetes and Goiter in the Medicine and Endocrinology Department of Mali Hospital.
[13]  Sidibé, E.H., Fall, L. and Sow, A.M. (1997) Clinical Features of Primary Hypothyroidism in Dakar: Report of 37 Cases. Cahiers d’études et de recherches francophones/Santé, 7, 291.
[14]  Simonin, R., Sambuc, R. and Solivares Donnat, J. (1984) Subclinical Hypothyroidism. Revue Française d'Endocrinologie Clinique, 25, 11-18.
[15]  Vanderpump, M.P. (2017) Epidemiology of Iodine Deficiency. Minerva Medica, 108, 116-123.
https://doi.org/10.23736/s0026-4806.16.04918-1
[16]  Wémeau, J. (2011) Prise en charge thérapeutique des goitres. La Presse Médicale, 40, 1147-1154.
https://doi.org/10.1016/j.lpm.2011.10.005

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