Primary squamous cell carcinoma of the breast is rare. We report a case of primary squamous cell carcinoma of the breast. It is a 47-year-old woman. She has an ulcerated, budding mass measuring 11 cm in diameter in the right breast. She underwent a right mastectomy. The diagnosis was non-keratinizing, moderately differentiated squamous cell carcinoma of the breast, stage IIIB invasive. Immunohistochemical testing was negative for estrogen and progesterone receptors but positive for cytokeratin CK 5/6. Diagnosis is histological and it is important to differentiate its primary breast origin from skin tumors or metastases from other organs.
References
[1]
Ahmed, Z., Idriss, A.M., Heiba, A. and Sidi, I. (2019) Carcinome épidermoïde du sein: À propos d’un cas en Mauritanie. PanAfricanMedicalJournal, 33, Article 143. https://doi.org/10.11604/pamj.2019.33.143.18375
[2]
Vidyasagar, M.S., Fernandes, D.J. and Ramanujam, A.S. (1998) Primary Squamous Cell Carcinoma of the Breast in a Young Woman: A Case Report and Review of Literature. Indian Journal of Pathology and Microbiology, 41, 485-488.
[3]
Stevenson, J.T., Graham, D.J., Khiyami, A. and Mansour, E.G. (1996) Squamous Cell Carcinoma of the Breast: A Clinical Approach. AnnalsofSurgicalOncology, 3, 367-374. https://doi.org/10.1007/bf02305666
[4]
Behranwala, K.A., Nasiri, N., Abdullah, N., Trott, P.A. and Gui, G.P.H. (2003) Squamous Cell Carcinoma of the Breast: Clinico-Pathologic Implications and Outcome. EuropeanJournalofSurgicalOncology (EJSO), 29, 386-389. https://doi.org/10.1053/ejso.2002.1422
[5]
Wrightson, W.R., Edwards, M.J. and Mcmasters, K.M. (1999) Primary Squamous Cell Carcinoma of the Breast Presenting as a Breast Abscess. TheAmericanSurgeon, 65, 1153-1155. https://doi.org/10.1177/000313489906501212
[6]
Zoltan, T.B., Konick, L. and Coleman, R.J. (2001) Pure Squamous Cell Carcinoma of the Breast in a Patient with Previous Adenocarcinoma of the Breast: A Case Report and Review of the Literature. TheAmericanSurgeon, 67, 671-673. https://doi.org/10.1177/000313480106700717
[7]
Tan, Y.M., Yeo, A., Chia, K.H. and Wong, C.Y. (2002) Breast Abscess as the Initial Presentation of Squamous Cell Carcinoma of the Breast. EuropeanJournalofSurgicalOncology (EJSO), 28, 91-93. https://doi.org/10.1053/ejso.2001.1156
[8]
Talmor, M., Rothaus, K.O., Shannahan, E., Cortese, A.F. and Hoffman, L.A. (1995) Squamous Cell Carcinoma of the Breast after Augmentation with Liquid Silicone Injection. AnnalsofPlasticSurgery, 34, 619-623. https://doi.org/10.1097/00000637-199506000-00009
[9]
Singh, H., Williams, S.P., Kinsella, V. and Lynch, G.R. (2000) Postradiation Squamous Cell Cancer of the Breast. CancerInvestigation, 18, 343-346. https://doi.org/10.3109/07357900009012177
[10]
Siegelmann-Danieli, N., Murphy, T.J., Meschter, S.C., Stein, M.E. and Prichard, J. (2005) Primary Pure Squamous Cell Carcinoma of the Breast. ClinicalBreastCancer, 6, 270-272. https://doi.org/10.3816/cbc.2005.n.030
[11]
Flikweert, E.R., Hofstee, M. and Liem, M.S. (2008) Squamous Cell Carcinoma of the Breast: A Case Report. WorldJournalofSurgicalOncology, 6, Article No. 135. https://doi.org/10.1186/1477-7819-6-135
[12]
Gupta, R.K. and Dowle, C.S. (1997) Cytodiagnosis of Pure Primary Squamous-Cell Carcinoma of the Breast by Fine-Needle Aspiration Cytology. Diagnostic Cytopathology, 17, 197-199. https://doi.org/10.1002/(sici)1097-0339(199709)17:3<197::aid-dc5>3.0.co;2-c
[13]
Carbone, S., Lobo Alvarez, R., Lamacchia, A., Almenar Gil, A., Martin Hernandez, R., Lopez Guerra, J.L., etal. (2012) Primary Squamous Cell Carcinoma of the Breast: A Rare Case Report. ReportsofPracticalOncology&Radiotherapy, 17, 363-366. https://doi.org/10.1016/j.rpor.2012.07.004
[14]
Anne, N., Sulger, E. and Pallapothu, R. (2019) Primary Squamous Cell Carcinoma of the Breast: A Case Report and Review of the Literature. JournalofSurgicalCaseReports, 2019, rjz182. https://doi.org/10.1093/jscr/rjz182
[15]
Tayeb, K., Saâdi, I., Kharmash, M., Hadadi, K., El Omari-Alaoui, H., El Ghazi, E., et al. (2002) Carcinome épidermoïde primitif du sein. À propos de 3 cas. Cancer /Radiothérapie, 6, 366-368. https://doi.org/10.1016/s1278-3218(02)00258-5
[16]
Cheng, Z., Han, T., Zhang, X., Li, X., Li, H. and Gu, J. (2019) Prognostic Factors for Breast Cancer Squamous Cell Carcinoma and Nomogram Development for Prediction: Population-Based Research. TranslationalCancerResearch, 8, 2014-2023. https://doi.org/10.21037/tcr.2019.09.13
