Inflammatory Fibroid Polyp: About Four Observations Including an Appendicular Localization

We report four observations of inflammatory fibroid polyps, including a rare case of appendicular localization. Two of our patients were female and two were male. They were aged 19, 24, 39, and 4 years, respectively. These were four cases discovered on surgical specimens after acute digestive episodes requiring laparotomy. Macroscopically, they were polypoid masses that developed at the expense of the submucosa. The polyp size ranged from 9 to 4 cm on the long axis. Microscopically, the masses were composed of spindle and/or star-shaped cells in a richly vascularized fibromyxoid chorion, reworked by a polymorphic infiltrate of predsominantly eosinophilic polynuclear cells. Immunohistochemically, tumor cells expressed high levels of CD34 with a very low Ki67 proliferation index. Inflammatory adenoid polyp is a rare benign lesion that can affect all segments of the digestive tract. Its pathogenesis is poorly understood and remains controversial. Its diagnosis can be difficult, especially on endoscopic biopsy, leading to its discussion with inflammatory lesions and certain spindle cell tumors of the digestive tract. It is treated surgically, with a good prognosis and no recurrence after total excision.