|
|
原发性肺腺癌术后胃转移1例
|
Abstract:
原发性肺腺癌术后胃转移较为罕见，且其症状不典型，容易漏诊和误诊。本文报道一例因纳差、黑便、贫血就诊的患者，最后诊断为肺腺癌胃转移的诊治过程，以提高临床医生对肺癌胃转移的认识和警惕。
Gastric metastasis of primary lung adenocarcinoma after surgery is rare and its symptoms are atypical, so it is easy to be missed and misdiagnosed. In this paper, we report a case of gastric metastasis of lung adenocarcinoma in a patient who was finally diagnosed with gastric metastasis of lung adenocarcinoma due to poor appetite, black stool and anemia, in order to raise the awareness and vigilance of clinicians on gastric metastasis of lung cancer.
| [1] | Niu, F., Zhou, Q., Yang, J., Zhong, W., Chen, Z., Deng, W., et al. (2016) Distribution and Prognosis of Uncommon Metastases from Non-Small Cell Lung Cancer. BMC Cancer, 16, Article No. 149. https://doi.org/10.1186/s12885-016-2169-5 |
| [2] | Yoshimoto, A., Kasahara, K. and Kawashima, A. (2006) Gastrointestinal Metastases from Primary Lung Cancer. European Journal of Cancer, 42, 3157-3160. https://doi.org/10.1016/j.ejca.2006.08.030 |
| [3] | Antler, A.S., Ough, Y., Pitchumoni, C.S., Davidian, M. and Thelmo, W. (1982) Gastrointestinal Metastases from Malignant Tumors of the Lung. Cancer, 49, 170-172. https://doi.org/10.1002/1097-0142(19820101)49:1<170::aid-cncr2820490134>3.0.co;2-a |
| [4] | Kim, M.S., Kook, E.H., Ahn, S.H., Jeon, S.Y., Yoon, J.H., Han, M.S., et al. (2008) Gastrointestinal Metastasis of Lung Cancer with Special Emphasis on a Long-Term Survivor after Operation. Journal of Cancer Research and Clinical Oncology, 135, 297-301. https://doi.org/10.1007/s00432-008-0424-0 |
| [5] | Lee, P. (2011) Role of Surgical Intervention in Managing Gastrointestinal Metastases from Lung Cancer. World Journal of Gastroenterology, 17, 4314-4320. https://doi.org/10.3748/wjg.v17.i38.4314 |
| [6] | Taira, N., Kawabata, T., Gabe, A., Furugen, T., Ichi, T., Kushi, K., et al. (2017) Analysis of Gastrointestinal Metastasis of Primary Lung Cancer: Clinical Characteristics and Prognosis. Oncology Letters, 14, 2399-2404. https://doi.org/10.3892/ol.2017.6382 |
| [7] | Kim, S.Y., Ha, H.K., Park, S.W., Kang, J., Kim, K.W., Lee, S.S., et al. (2009) Gastrointestinal Metastasis from Primary Lung Cancer: CT Findings and Clinicopathologic Features. American Journal of Roentgenology, 193, W197-W201. https://doi.org/10.2214/ajr.08.1907 |
| [8] | Ishikawa, E., Nakaguro, M., Nakamura, M., Yamamura, T., Sawada, T., Mizutani, Y., et al. (2020) Gastrointestinal Tract Metastasis of Lung Cancer: The PD-L1 Expression and Correlated Clinicopathological Variables. Pathology International, 71, 33-41. https://doi.org/10.1111/pin.13048 |
| [9] | He, Y., Cui, Y., Duan, X., Liu, C. and Cai, X. (2018) Primary Lung Squamous Cell Carcinoma with Gastric Metastasis: A Case Report. Thoracic Cancer, 10, 373-377. https://doi.org/10.1111/1759-7714.12940 |
| [10] | Oda, I., Kondo, H., Yamao, T., Saito, D., Ono, H., Gotoda, T., et al. (2001) Metastatic Tumors to the Stomach: Analysis of 54 Patients Diagnosed at Endoscopy and 347 Autopsy Cases. Endoscopy, 33, 507-510. https://doi.org/10.1055/s-2001-14960 |
| [11] | Palma, G.D.D. (2006) Metastatic Tumors to the Stomach: Clinical and Endoscopic Features. World Journal of Gastroenterology, 12, 7326-7328. https://doi.org/10.3748/wjg.v12.i45.7326 |
| [12] | Dassen, A.E., Lips, D.J., Hoekstra, C.J., Pruijt, J.F.M. and Bosscha, K. (2009) FDG-PET Has No Definite Role in Preoperative Imaging in Gastric Cancer. European Journal of Surgical Oncology, 35, 449-455. https://doi.org/10.1016/j.ejso.2008.11.010 |
| [13] | Whithaus, K., Fukuoka, J., Prihoda, T.J. and Jagirdar, J. (2012) Evaluation of Napsin A, Cytokeratin 5/6, P63, and Thyroid Transcription Factor 1 in Adenocarcinoma versus Squamous Cell Carcinoma of the Lung. Archives of Pathology & Laboratory Medicine, 136, 155-162. https://doi.org/10.5858/arpa.2011-0232-oa |
| [14] | Rossi, G., Marchioni, A., Romagnani, E., Bertolini, F., Longo, L., Cavazza, A., et al. (2007) Primary Lung Cancer Presenting with Gastrointestinal Tract Involvement: Clinicopathologic and Immunohistochemical Features in a Series of 18 Consecutive Cases. Journal of Thoracic Oncology, 2, 115-120. https://doi.org/10.1016/s1556-0864(15)30037-x |
| [15] | Wu, Q., Luo, W., Zhao, Y., Xu, F. and Zhou, Q. (2017) The Utility of 18F-FDG PET/CT for the Diagnosis of Adrenal Metastasis in Lung Cancer. Nuclear Medicine Communications, 38, 1117-1124. https://doi.org/10.1097/mnm.0000000000000757 |
| [16] | Hu, Y., Feit, N., Huang, Y., Xu, W., Zheng, S. and Li, X. (2018) Gastrointestinal Metastasis of Primary Lung Cancer: An Analysis of 366 Cases. Oncology Letters, 15, 9766-9776. https://doi.org/10.3892/ol.2018.8575 |
| [17] | Katsenos, S. and Archondakis, S. (2013) Solitary Gastric Metastasis from Primary Lung Adenocarcinoma: A Rare Site of Extra-Thoracic Metastatic Disease. Journal of Gastrointestinal Oncology, 4, E11-E15. |
| [18] | Ellis, L.M., Bernstein, D.S., Voest, E.E., Berlin, J.D., Sargent, D., Cortazar, P., et al. (2014) American Society of Clinical Oncology Perspective: Raising the Bar for Clinical Trials by Defining Clinically Meaningful Outcomes. Journal of Clinical Oncology, 32, 1277-1280. https://doi.org/10.1200/jco.2013.53.8009 |
