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免疫细胞在骨折愈合的研究进展及其发展前景
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Abstract:
骨折损伤发生后，最初的炎症反应可能对骨折修复具有促进的作用。然而，过度炎症对这一过程可能具有延缓作用，迄今为止，很少有研究能够明确阐明某些免疫细胞在骨折愈合中的作用，鉴于骨折愈合并发症的高度临床相关性，这种知识的缺乏尤其引人注目。本文就免疫细胞在骨愈合的研究进展及其发展前景作一综述，拟为揭示免疫细胞在骨组织损伤修复中的调控作用。
Following a fracture, the initial inflammatory response may promote the healing process. However, excessive inflammation can delay this process. To date, few studies have clearly elucidated the roles of specific immune cells in fracture healing. Given the high clinical relevance of fracture healing complications, this knowledge gap is particularly noteworthy. This review provides a comprehensive overview of the research progress on immune cells in bone healing and discusses future prospects, aiming to shed light on the regulatory roles of immune cells in bone tissue repair.
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