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Medical Diagnosis 2025
II/III期结直肠癌术后血清CEA变化与预后的相关性研究
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Abstract:
结直肠癌(CRC)是全球高发的恶性肿瘤之一，术后复发是影响患者预后的重要因素。癌胚抗原(CEA)作为CRC临床管理中应用最广泛的肿瘤标志物，其术后动态变化与肿瘤复发密切相关。本文通过综述现有研究，系统探讨II/III期结直肠癌患者术后血清CEA水平的变化模式及其对肿瘤复发的预测价值，分析其在临床应用中的实际价值，并展望未来研究方向，以期为优化术后监测策略提供理论依据。
Colorectal cancer (CRC) is one of the most frequently occurring malignant tumors worldwide, and postoperative recurrence is a significant factor affecting patient prognosis. Carcinoembryonic antigen (CEA), as the most widely used tumor marker in the clinical management of CRC, is closely related to tumor recurrence through its dynamic changes postoperatively. This paper systematically reviews existing studies to explore the change patterns of postoperative serum CEA levels in patients with stage II/III colorectal cancer and their predictive value for tumor recurrence. It analyzes the practical value of CEA in clinical applications and prospects future research directions, aiming to provide a theoretical basis for optimizing postoperative monitoring strategies.
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