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卟啉基金属有机框架材料及其在传感检测的研究进展与展望
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Abstract:
卟啉基金属有机框架材料(PMOFs)相比于传统传感材料(如酶、抗体)具有更高的比表面积、优异的光电活性、可调孔径及良好的生物相容性，在传感检测领域展现出了独特优势。本文系统综述了PMOFs的关于金属中心调控、卟啉功能化修饰、混合配体设计策略以及后合成修饰、复合功能化等功能化方法。探讨了PMOFs目前在荧光、比色、电化学及光电化学等传感检测中的应用进展。概括描述了PMOFs在未来发展的方向。譬如其目前在稳定性、规模化制备等方面仍面临挑战，在未来发展方向应往多模态传感融合、智能响应材料开发及结合人工智能技术来发展。为PMOFs的实际传感检测应用提供了理论支持和技术参考。
Porphyrin-based organic framework materials (PMOFs) have higher specific surface area, excellent photoelectric activity, adjustable pore size and good biocompatibility compared with traditional sensing materials (such as enzymes and antibodies), which have shown unique advantages in the field of sensing and detection. In this paper, the functionalization methods of PMOFs, such as metal center regulation, porphyrin functionalization, hybrid ligand design strategies, post-synthetic modification, and complex functionalization, are systematically reviewed. The current application progress of PMOFs in fluorescence, colorimetric, electrochemical and photoelectrochemical sensing detection is discussed. The direction of PMOFs development in the future is summarized. For example, it still faces challenges in stability and large-scale preparation. In the future, the development direction should be developed towards multimodal sensor fusion, intelligent response material development, and combination with artificial intelligence technology. This study provides theoretical support and technical reference for the practical sensing application of PMOFs.
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