Summary: Deep vein thrombosis (DVT) and pulmonary embolism (PE) are two entities of venous thromboembolism (VTE) whose incidence is difficult to assess. Objective: This paper aims to evaluate the prevalence of venous thromboembolism. Patients and Methods: This was a descriptive cross-sectional study with prospective collection, over 12 months from May 1, 2023 to April 30, 2024. Results: We admitted 627 patients including 6 cases of VTE, with a prevalence of 096%. The average age was 49.67 ± 17.58 years with extremes of 30 to 71 years, the sex ratio 0.2, and housewives represented 33.3%. The transient risk factors (FDR) were prolonged immobilization ≥ 05 days (05 cases) 83.3%, major surgery (01 case) 16.7%, spinal cord trauma (01 case) 16.7%, central venous catheter (04 cases) 66.6%; the permanent risk factors (FDR) were obesity (04 cases) 66.6%, age (3 cases) 50%, high blood pressure (hypertension) (3 cases) 50%, cancer (01 case) 16.7%. The main clinical signs were dyspnea (100%), tachycardia (33.3%), chest pain (33.3%), and Homans sign with increased local heat (01 cases) 16.7%. The diagnoses retained were PE (04 cases) 83.3%, PE + DVT (01 case) 16.7% and DVT (01 case) 16.7%. All patients were placed on oxygen therapy, (02 cases) intubated and ventilated, (02 cases) High Flow Oxygenation, (02 cases) on amines such as dobutamine + norepinephrine and norepinephrine alone (83.3%) of patients were placed on direct oral anticoagulants (DOACs) and 16.7% on low molecular weight heparin (LMWH). The average length of stay was 7.3 ± 3.33 days with extremes of 4 to 13 days and the lethality of (03 cases) 50% of which (02 cases) had sPESI ≥ 2. Conclusion: The diagnosis and management of VTE remains difficult and responsible for significant morbidity and mortality.
References
[1]
Caillard, G. and Clerel, M. (2001) Travel and Risk of Venous Thrombosis. TheLancet, 357, 554-555. https://doi.org/10.1016/s0140-6736(05)71698-6
[2]
Oger, E., Lacut, K. and Scarabin, P.Y. (2002) Thrombose veineuse profonde: Épidemiologie, facteurs de risque acquis. AnnalesdeCardiologieetd’Angéiologie, 51, 124-128. https://doi.org/10.1016/s0003-3928(02)00083-5
[3]
Djénakpo, J.L., Zoumènou, E., Kérékou, A., Dossou, F., Hounton, N., Sambiéni, O., et al. (2012) Fréquence et facteurs de risque de la maladie thromboembolique veineuse chez la femme en milieu hospitalier à Cotonou, Benin. Ashdin Publishing Clinics in Mother and Child Health, 9, Article ID: C120202. https://doi.org/10.4303/cmch/C120202
[4]
Owono Etoundi, P., Esiéne, A., Bengono Bengono, R., Amengle, L., Afane Ela, A. and Ze Minkande, J. (2015) La Maladie Thromboembolique Veineuse. Aspects Épidémiologiques et Facteurs de Risque dans un Hôpital Camerounais. Health Sciences and Disease, 16, 1-4.
[5]
Bertrand, E., Charle, D., Chouvet, J., Coulibaly, A.O., etal. (1979) Précis de pathologie cardiovasculaire Tropicale, de la rareté de la pathologie thrombo-embolique en région tropicale. Paris Sandoz.
[6]
Coulibaly, S., Menta, I., Diall, I.B., etal. (2018) Maladie Thromboembolique Veineuse dans le Ser-vice de Cardiologie du CHU du Point G à Bamako. Health Sciences and Disease, 19, 27-30.
[7]
Germini, F., Zarabi, S., Eventov, M., Turcotte, M., Li, M. and de Wit, K. (2021) Prévalence de l’embolie pulmonaire parmi les cohortes des services d’urgence: Revue systématique et méta-analyse. Journal of Thrombosis and Haemostasis, 19, 173-185. https://doi.org/10.1111/jth.15124
[8]
Zarabi, S., Chan, T.M., Mercuri, M., Kearon, C., Turcotte, M., Grusko, E., etal. (2021) Physician Choices in Pulmonary Embolism Testing. CanadianMedicalAssociationJournal, 193, E38-E46. https://doi.org/10.1503/cmaj.201639
[9]
Menta, I., Ba, H.O., Coulibaly, S., etal. (2019) Venous Thromboembolism in Hospitalization in the Cardiology Department of University Hospital Gabriel Toure. ArchivesofCardiologyandCardiovascularDiseases, 2, 1-7.
[10]
Mahé, I., Caulin, C. and Bergmann, J.-F. (2005) L’âge, un facteur indépendant de risque de thrombose. LaPresseMédicale, 34, 878-886. https://doi.org/10.1016/s0755-4982(05)84068-0
[11]
Chalal, N. and Demmouche, A. (2013) Maladie thromboembolique veineuse dans la région de Sidi Bel Abbes, Algérie: Fréquence et facteurs de risque. PanAfricanMedicalJournal, 16, Article 45. https://doi.org/10.11604/pamj.2013.16.45.2620
[12]
Samama, M.M., Cohen, A.T., Darmon, J., Desjardins, L., Eldor, A., Janbon, C., etal. (1999) A Comparison of Enoxaparin with Placebo for the Prevention of Venous Thromboembolism in Acutely Ill Medical Patients. NewEnglandJournalofMedicine, 341, 793-800. https://doi.org/10.1056/nejm199909093411103
[13]
Bernasconi, F., Estrade, G., Garnier, D. and Donatien, Y. (1988) Aspect actuel de la maladie thromboembolique en Martinique à propos de 46 cas. Caraïbes Medical, 24, 160-165.
[14]
Heit, J.A., Silverstein, M.D., Mohr, D.N., Petterson, T.M., O’Fallon, W.M. and Melton, L.J. (2000) Risk Factors for Deep Vein Thrombosis and Pulmonary Embolism. ArchivesofInternalMedicine, 160, 809-815. https://doi.org/10.1001/archinte.160.6.809
[15]
Isma, N., Svensson, P.J., Gottsäter, A. and Lindblad, B. (2009) Prospective Analysis of Risk Factors and Distribution of Venous Thromboembolism in the Population-Based Malmö Thrombophilia Study (MATS). ThrombosisResearch, 124, 663-666. https://doi.org/10.1016/j.thromres.2009.04.022
[16]
Bergqvist, D. (1983) Frequency of Thromboembolic Complications. In: Bergqvist, D., Ed., PostoperativeThromboembolism, Springer, 6-34. https://doi.org/10.1007/978-3-642-68863-8_2
[17]
Kahn, S.R. and de Wit, K. (2022) Pulmonary Embolism. NewEnglandJournalofMedicine, 387, 45-57. https://doi.org/10.1056/nejmcp2116489