Melanomas of the urinary tract are rare aggressive cancers, often with very poor prognoses. We report a case of primary melanoma of the female urethra in a 69-year-old female farmer who was referred for the management of a vulvar mass associated with dysuria and urinary frequency. Clinical examination revealed a blackish mass measuring approximately 4 cm at the distal end of the urethra, mobile with necrotic and purulent plaques, bleeding on contact. The anterior vaginal wall was not involved. Diagnostic cystoscopy showed mild bladder trabeculations. A CT scan of the thorax, abdomen and pelvis did not reveal any distant metastases. The mass was resected after a straightforward procedure. The diagnosis was established after a histopathology report. We discuss this case as we review the literature relevant to the case.
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