Background: Life review has potential to improve psychological distress of cancer patients. However, there are some problems with geography or chances to receive therapy. We needed to develop a new style of life review. Purpose: The purpose of this study was to develop an AI Life Review program, and to investigate the feasibility and utility of it on psychological distress and well-being. Method: Participants were advanced cancer patients. We made an AI Life Review application. In the first session, a patient reviewed his life using the AI Life Review application. The researcher made a life review book based on his review. After two weeks, the patient confirmed the book in the second session. The patient completed questionnaires about psychological distress by the HADS measuring anxiety and depression, and well-being by FACIT-Sp measuring spirituality, Gratitude, Hope, and Life Satisfaction. Results: The Anxiety score significantly decreased from 4.67 to 2.60 (p < 0.01), the Depression score also significantly decreased from 6.93 to 4.67 (p < 0.05). The FACIT-Sp score significantly increased from 28.2 to 30.9 (p < 0.05), the Gratitude score significantly increase from 27.4 to 30.3 (p < 0.01), and the Hope score significantly increased from 5.07 to 5.73 (p < 0.05). The Life Satisfaction score didn’t change. The categories of main themes in narratives in life review were chosen. Conclusion: These results suggest that the AI Life Review application program has the potential to apply for advanced cancer patients and useful on psychological distress like anxiety and depression, and well-being life spirituality, gratitude, and hope.
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