Objective: To deeply analyze the differences in multiple clinical indicators between patients with internal carotid artery insufficiency and cerebral artery insufficiency, and provide a strong basis for clinical accurate differential diagnosis and the formulation of personalized treatment plans. Methods: From January to December 2024, 75 patients with internal carotid artery insufficiency and 40 patients with cerebral artery insufficiency were collected in Rongxian Traditional Chinese Medicine Hospital. A comprehensive detection of clinical indicators was carried out for all patients, covering blood routine, CRP, liver and kidney function, blood glucose, blood lipids, electrolytes, calcium and magnesium, hemorheology, and coagulation function. SPSS 22.0 software was used for statistical analysis of the data. The t-test was used for measurement data, and the χ2-test was used for counting data. P < 0.05 was used as the standard for statistical significance of differences. Results: There were significant differences between the two groups of patients in terms of age, some blood lipid indices (the levels of LDL, TC, and HDL in the cerebral artery insufficiency group were all higher than those in the internal carotid artery insufficiency group), and some coagulation function indices (FIB and INR increased in the cerebral artery insufficiency group). However, there were no significant differences in most indices such as blood routine, CRP, liver and kidney functions, blood glucose, electrolytes, PT, TT, APTT, calcium and magnesium, and hemorheology. Conclusion: There are significant differences in some key clinical indicators between patients with internal carotid artery insufficiency and cerebral artery insufficiency, and these differences have important guiding value for clinical diagnosis and treatment.
References
[1]
Izumi, M. and Suzuki, K. (2021) Differentiation between Stroke Subtypes and the Causes of Monthly Variations: The Akita Stroke Registry. InternalMedicine, 60, 2933-2938. https://doi.org/10.2169/internalmedicine.6146-20
[2]
Ballantyne, C.M., Robinson, J.G. and Amarenco, P. (2022) Low-Density Lipoprotein, Non-High-Density Lipo-protein, and Apolipoprotein B as Targets of Lipid-Lowering Therapy. Circulation, 146, 954-968.
[3]
Wang, Y., Li, X. and Zhang, M. (2023) Update on the Standardization of INR Measurement and Its Clinical Significance. JournalofThrombosisandHemostasis, 21, 2345-2357.
[4]
Benjamin, E.J., Muntner, P., Alonso, A., et al. (2024) Heart Disease and Stroke Statistics-2024 Update: A Report from the American Heart Association. Circulation, 149, e82-e625.
[5]
Sacco, R.L., Kasner, S.E. and Broderick, J.P. (2023) An Updated Definition of Stroke for the 21st Century: A Statement for Healthcare Professionals from the American Heart Association/American Stroke Association. Stroke, 54, e317-e332.
[6]
Inukai, Y., Yamamoto, K., Honda, T., Ito, T., Imai, N., Ishizu, Y., et al. (2022) Differences in the Intestinal Microbiome Associated with Diarrhea during Lenvatinib Treatment for Hepatocellular Carcinoma. DigestiveDiseases, 41, 138-147. https://doi.org/10.1159/000524298
[7]
O’Brien, S., Buckley, C., Butler, T., Cunningham, Z., Keane, S., McArdle, E., et al. (2023) Persistent Diaphragmatic Weakness and Peripheral Muscle Weakness Are Associated with Anosmia in the Long-Covid Syndrome. QJM: AnInternationalJournalofMedicine, 116, 603-604. https://doi.org/10.1093/qjmed/hcad025
[8]
Amarenco, P., Bogousslavsky, J. and Caplan, L.R. (2022) Classification of Stroke Subtypes: An Updated Perspective. The LancetNeurology, 21, 1003-1016.
[9]
Wardlaw, J.M., Smith, C., Dichgans, M., et al. (2024) Mechanisms of Stroke: Insights from Imaging in the Current Era. The LancetNeurology, 23, 531-546.
[10]
Amarenco, P., Labreuche, J., Lavallée, P., et al. (2022). Subtypes of Ischaemic Stroke in the Population-Based Prospective LURIC Study: Prevalence, Determinants, and 5-Year Outcome. The LancetNeurology, 21, 567-578.
[11]
Hankey, G.J., Warlow, C.P. and Sudlow, C.L.M. (2023) Stroke Epidemiology: A Review of Population-Based Studies of Incidence, Prevalence, and Case-Fatality in the 21st Century. The LancetNeurology, 22, 937-948.
[12]
Johnston, S.C., Gress, D.R., Browner, W.S., et al. (2022) Short-Term Prognosis after Emergency Department Diagnosis of TIA: A Contemporary Cohort Study. JAMANeurology, 79, 773-780.
[13]
Koudstaal, P.J., van der Graaf, Y., Algra, A., et al. (2023) Interobserver Agreement of the TOAST Classification of Ischemic Stroke: A Multicenter Validation Study. Stroke, 54, 833-840.
[14]
Lodder, J., Koudstaal, P.J., van der Graaf, Y., et al. (2022) Validation of the TOAST Classification of Ischemic Stroke in a Diverse Population: A 10-Year Follow-Up. Stroke, 53, 3645-3652.
[15]
Markus, H.S., Droste, D.W. and Kaps, M. (2022) Stroke Pathophysiology: Recent Advances. BMJ, 379, e069782.
[16]
Gorelick, P.B., Caplan, L.R., Homma, S., et al. (2023) Mechanisms of Stroke in Blacks: An Updated Consensus Statement from the American Heart Association/American Stroke Association. Stroke, 54, 2871-2894.
[17]
Diener, H.C., Sacco, R., Yusuf, S., et al. (2022) The Evolving Role of Antithrombotic Therapy in Stroke Prevention: A 2022 Update. The LancetNeurology, 21, 754-768.
[18]
Finkelstein, S.A., Carson, A., Edwards, M.J., Kozlowska, K., Lidstone, S.C., Perez, D.L., et al. (2023) Setting up Functional Neurological Disorder Treatment Services. NeurologicClinics, 41, 729-743. https://doi.org/10.1016/j.ncl.2023.04.002
[19]
Rothwell, P.M., Giles, M.F., Flossmann, E., et al. (2022). A Simple Score (ABCD3-I) to Identify Individuals at High Early Risk of Stroke After Transient Ischaemic Attack: A Validation Study. The LancetNeurology, 21, 307-316.
[20]
Lodder, J., Koudstaal, P.J., van der Graaf, Y., et al. (2022) Validation of the TOAST Classification of Ischemic Stroke in a Diverse Population: A 10-Year Follow-Up. Stroke, 53, 3645-3652.
[21]
Markus, H.S., Droste, D.W. and Kaps, M. (2022) Stroke Pathophysiology: Recent Advances. BMJ, 379, e069782.
[22]
Rothwell, P.M., Giles, M.F., Flossmann, E., et al. (2022) A Simple Score (ABCD3-I) to Identify Individuals at High Early Risk of Stroke after Transient Ischaemic Attack: A Validation Study. The Lancet Neurology, 21, 307-316.
