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多种评分系统对于急性重症胰腺炎器官功能衰竭的预测价值
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Abstract:
急性胰腺炎(AP)是临床上最常见的消化系统疾病之一。SAP患者主要死亡原因为感染和多器官功能衰竭。目前，临床上有多种评分系统被用于评估AP的严重程度和预后，包括BISAP、APACHE II、Ranson、SOFA、qSOFA、HAPS和OASIS等评分系统。这些评分系统各有优劣，例如BISAP操作简便但灵敏度较低，APACHE II预测准确性高但复杂耗时，Ranson评分存在时间滞后性，SOFA和qSOFA在ICU中表现优异，HAPS在预测非重症AP方面具有高度特异性，而OASIS作为一种新兴评分系统，在ICU患者预后预测中展现出潜力。尽管这些评分系统在临床应用中存在各自的优劣势，但其早期及时应用有助于精准评估疾病严重程度，制定个体化治疗方案，改善患者预后。未来需进一步开展多中心研究，优化评分系统的准确性和实用性，以提升AP患者的生存率和治疗效果。
Acute pancreatitis (AP) is one of the most common digestive system diseases in clinical practice. The primary causes of death in severe acute pancreatitis (SAP) patients are infection and multiple organ failure. Currently, there are multiple scoring systems used in clinical settings to assess the severity and prognosis of AP, including the BISAP, APACHE II, Ranson, SOFA, qSOFA, HAPS, and OASIS scoring systems. Each of these systems has its strengths and weaknesses. For example, BISAP is simple to use but has low sensitivity, APACHE II offers high predictive accuracy but is complex and time-consuming, Ranson scores suffer from time lag, SOFA and qSOFA perform excellently in ICU settings, HAPS is highly specific for predicting non-severe AP, and OASIS, as an emerging scoring system, shows potential in predicting ICU patient outcomes. Despite their respective advantages and disadvantages in clinical application, the early and timely use of these scoring systems can help accurately assess disease severity, formulate individualized treatment plans, and improve patient prognosis. Future efforts should focus on multicenter studies to optimize the accuracy and practicality of these scoring systems, thereby enhancing the survival rates and treatment outcomes of AP patients.
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