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脑小血管疾病的危险因素和发病机制
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Abstract:
脑小血管病(CSVD)是一种大脑微血管疾病，可破坏血脑屏障，影响脑部组织的微循环，导致脑组织局部病变的疾病。这种疾病占缺血性卒中的20%~25%，也是痴呆的45%左右的常见原因，但其发病机制尚不清楚，本文对目前主要的脑小血管病的病因及发病机制进行综述，为临床对该病的诊治提供参考。
Cerebral small vessel disease (CSVD) is a type of cerebral microvascular disease that can damage the blood-brain barrier, affect microcirculation in brain tissue, and lead to local lesions in brain tissue. This disease accounts for 20%~25% of ischemic stroke and is also a common cause of about 45% of dementia, but its pathogenesis is still unclear. This article reviews the etiology and pathogenesis of the main cerebral small vessel diseases, providing reference for clinical diagnosis and treatment of this disease.
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