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胃食管反流病的药物及内镜治疗的现状
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Abstract:
胃食管反流病(Gastroesophageal Reflux Disease, GERD)是一种常见的消化系统疾病，其治疗包括药物和内镜治疗。质子泵抑制剂(Proton Pump Inhibitors, PPIs)仍是主要药物，钾–氢泵抑制剂(Potassium-Competitive Acid Blockers, P-CABs)等新型药物逐步应用。内镜治疗技术不断发展，为药物难治性GERD提供了新选择。本文综述GERD的药物及内镜治疗的现状，分析其疗效、局限性，并展望未来发展方向，以期为临床治疗提供参考。
Gastroesophageal Reflux Disease (GERD) is a common digestive disorder, with treatment strategies including pharmacological and endoscopic therapies. Proton Pump Inhibitors (PPIs) are still the main drugs, while novel agents such as Potassium-Competitive Acid Blockers (P-CABs) are increasingly utilized. Advances in endoscopic techniques offer new therapeutic options for drug-refractory GERD. This review summarizes the current status of pharmacological and endoscopic treatments for GERD, discusses their efficacy and limitations, and explores future perspectives to provide a reference for clinical treatment.
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