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脓毒症分型的研究进展
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Abstract:
脓毒症是由感染引起的失调的宿主反应而导致危害生命的器官功能障碍的一组综合征，脓毒症患者存在明显的异质性，深入认识临床表现的异质性，甚至在基因层面的异质性，才有助于脓毒症患者的不良预后的早期识别和决策最佳治疗手段。众多学者就脓毒症的异质性而言，已从脓毒症的各个角度开展了分型研究，现综合近年来国内外各个学者的分型结果作一综述，以期对脓毒症的分型提供更广阔的选择。
Sepsis is a group of syndromes caused by a dysregulated host response to infection, leading to life-threatening organ dysfunction. Sepsis patients exhibit significant heterogeneity. A deeper understanding of the clinical heterogeneity, and even the genetic heterogeneity, is crucial for early identification of poor prognosis and the decision-making of optimal treatment strategies for sepsis patients. Numerous scholars have conducted classification studies on sepsis from various perspectives as far as the heterogeneity of sepsis is concerned, and this review summarizes the classification results from scholars at home and abroad in recent years, aiming to provide a broader range of options for the classification of sepsis.
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