Introduction: Uterine prolapse is a common condition among elderly and reproductive-aged women. It causes various physical, emotional and social limitations. The objective of this work was to determine the prevalence and risk factors associated with uterine prolapse in Butembo, a low-income setting. Materials and Methods: This was a case-control study that was conducted in Butembo from January 1 to September 30, 2024 with 48 patients with uterine prolapse and 134 patients with other pelvic static disorders, considered as controls. The data collected were entered into Microsoft Office LTSC 2021 Excel software and analyzed using R software version 4.4.0. We performed bivariate analyses and calculated odds ratios using the logistic regression method. The significance threshold was set at p < 0.05. Results: The prevalence of uterine prolapse was 6.7%. The age group of patients aged 50 to 84 years (OR = 2.36; p-value = 0.043), the rural place of origin (OR = 6.06; p-value < 0.001) and the marital status of widows (OR = 5.85; p-value < 0.001) significantly multiplied the risk of occurrence of uterine prolapse. The same is true for obstetric factors such as parity (OR = 1.32; p-value < 0.001), history of delivery of a macrosomia newborn (OR = 9.83; p-value < 0.001) and use of the Cristeler method during delivery (OR = 10.9; p-value < 0.001) and other factors such as overweight/obesity (OR = 4.54; p-value = 0.007) and chronic cough (OR = 3.12; p-value = 0.004). Conclusion: Uterine prolapse is a common pathology in Butembo and the associated risk factors are the age of the patients, the rural background, multiparity, the history of vaginal delivery with fetal macrosomia, the use of the Cristeler method during delivery.
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