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IP-10与PWH的相关性研究进展
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Abstract:
虽然目前公认抗逆转录病毒治疗(antiretroviral therapy, ART)可以延长HIV感染者(People with HIV, PWH)生存时间及改善生活质量，但持续存在的免疫激活将导致HIV相关非AIDS并发症的进一步发生。γ-干扰素诱导蛋10 (interferon gamma-induced protein 10, IP-10)是一种或在免疫系统中发挥着关键作用的炎症趋化因子，目前在国内外的PWH研究中得到广泛关注。
It is now well established that antiretroviral therapy (ART) can prolong the survival time and improve the quality of life of people with HIV (PWH), but persistent immune activation remains a significant concern, leading to the further development of HIV-related non-AIDS complications. Interferon gamma-induced protein 10 (IP-10), an inflammatory chemokine that plays a crucial role in the immune system, has garnered considerable attention in both domestic and international research on PWH.
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