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特应性皮炎合并单眼圆锥角膜一例
A Case of Atopic Dermatitis Combined with Monocular Keratoconus

DOI: 10.12677/jcpm.2025.41086, PP. 594-598

Keywords: 特应性皮炎,圆锥角膜
Atopic Dermatitis
, Keratoconus

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Abstract:

1例19岁男生因右眼视力下降3月就诊,患者既往过敏性鼻炎病史,2年前躯干、四肢逐渐出现红斑、丘疹、丘疱疹伴瘙痒,且反复发作,长期口服泼尼松片及乌帕替尼缓释片并外涂克立硼罗软膏治疗。检查见:右眼颞下方旁中央角膜锥形扩张,Munson征阳性,未见Fleischer征、Vogt线纹,右眼角膜变薄,但左眼未见明显异常。诊断为特应性皮炎合并右眼圆锥角膜,于外院行右眼角膜胶原交联术,术后随诊3个月病情稳定。
A 19-year-old male patient presented with a history of allergic rhinitis due to decreased vision in his right eye for 3 months. Two years ago, the patient gradually developed erythema, papules, and papules with itching on the trunk and limbs, and had recurrent episodes. The patient was treated with long-term oral prednisone tablets and sustained-release Upatinib tablets, as well as topical application of Cleboride ointment. Examination shows: Conical dilation of the central cornea below the temporal lobe in the right eye, positive Munson sign, no Fleischer sign or Vogt lines, thinning of the cornea in the right eye, but no obvious abnormalities in the left eye. Diagnosed with atopic dermatitis combined with keratoconus in the right eye, underwent corneal cross-linking surgery in an external hospital for the right eye, and the condition remained stable after 3 months of follow-up.

References

[1]  Hsu, J.I., Pflugfelder, S.C. and Kim, S.J. (2019) Ocular Complications of Atopic Dermatitis. Cutis, 104, 189-193.
[2]  Chang, Y., Weng, S., Wang, J., Tseng, S., Wang, J., Jan, H., et al. (2020) Association between Keratoconus and the Risk of Adolescent‐ or Adult‐Onset Atopic Dermatitis. Allergy, 75, 2946-2948.
https://doi.org/10.1111/all.14320

[3]  陈璐, 赵莹, 黄江, 等. 特应性皮炎的眼部并发症[J]. 中国皮肤性病学杂志, 2021, 35(10): 1193-1197.
[4]  魏熙翔, 杨晖, 尹雪, 等. 基于双样本孟德尔随机化的特应性皮炎与圆锥角膜因果关系研究[J]. 中华眼视光学与视觉科学杂志, 2023, 25(11): 860-865.
[5]  Shajari, M., Eberhardt, E., Müller, M., Al Khateeb, G., Friderich, S., Remy, M., et al. (2016) Effects of Atopic Syndrome on Keratoconus. Cornea, 35, 1416-1420.
https://doi.org/10.1097/ico.0000000000000935

[6]  Koh, S. and Nishida, K. (2019) Acute Corneal Hydrops in Keratoconus with Atopic Dermatitis. Mayo Clinic Proceedings, 94, 2053.
https://doi.org/10.1016/j.mayocp.2019.04.025

[7]  Zhou, W., Cai, J., Li, Z. and Lin, Y. (2023) Association of Atopic Dermatitis with Conjunctivitis and Other Ocular Surface Diseases: A Bidirectional Two‐Sample Mendelian Randomization Study. Journal of the European Academy of Dermatology and Venereology, 37, 1642-1648.
https://doi.org/10.1111/jdv.19048

[8]  McMonnies, C.W. (2009) Mechanisms of Rubbing-Related Corneal Trauma in Keratoconus. Cornea, 28, 607-615.
https://doi.org/10.1097/ico.0b013e318198384f

[9]  Xu, H., Wen, Y., Zheng, H., Jiang, D. and Chen, W. (2024) Allergic Disease and Keratoconus: A Two-Sample Univariable and Multivariable Mendelian Randomization Study. World Allergy Organization Journal, 17, Article 100993.
https://doi.org/10.1016/j.waojou.2024.100993

[10]  Droitcourt, C., Touboul, D., Ged, C., Ezzedine, K., Cario-André, M., de Verneuil, H., et al. (2011) A Prospective Study of Filaggrin Null Mutations in Keratoconus Patients with or without Atopic Disorders. Dermatology, 222, 336-341.
https://doi.org/10.1159/000328408

[11]  Rønnstad, A.T.M., Hansen, P.M., Halling, A.S., Egeberg, A., Kolko, M., Heegaard, S., et al. (2021) Factors Associated with Ocular Surface Disease and Severity in Adults with Atopic Dermatitis: A Nationwide Survey. Journal of the European Academy of Dermatology and Venereology, 36, 592-601.
https://doi.org/10.1111/jdv.17832

[12]  Beck, K.M., Seitzman, G.D., Yang, E.J., Sanchez, I.M. and Liao, W. (2019) Ocular Co-Morbidities of Atopic Dermatitis. Part I: Associated Ocular Diseases. American Journal of Clinical Dermatology, 20, 797-805.
https://doi.org/10.1007/s40257-019-00455-5

[13]  Kothari, N., Young, R.C., Read, S.P., Tutiven, J., Perez, V.L., Flynn, H.W., et al. (2017) Retinal Detachment Associated with Atopic Dermatitis. Ophthalmic Surgery, Lasers and Imaging Retina, 48, 513-517.
https://doi.org/10.3928/23258160-20170601-12

[14]  郑传珍, 任新军, 温德佳, 等. 青少年Andogsky综合征合并视网膜脱离二例[J]. 中华眼科杂志, 2020, 56(4): 299-302.
[15]  Thyssen, J.P., Toft, P.B., Halling-Overgaard, A., Gislason, G.H., Skov, L. and Egeberg, A. (2017) Incidence, Prevalence, and Risk of Selected Ocular Disease in Adults with Atopic Dermatitis. Journal of the American Academy of Dermatology, 77, 280-286.E1.
https://doi.org/10.1016/j.jaad.2017.03.003

[16]  Hajdarbegovic, E., Kamphuis, L., van Laar, J., van Hagen, M., Nijsten, T. and Thio, B. (2014) Prevalence of Atopic Diseases in Patients with Sarcoidosis. Allergy and Asthma Proceedings, 35, 354-354.
https://doi.org/10.2500/aap.2014.35.3754

[17]  董慧, 刘佳, 赵天祺, 圆锥角膜的预防及治疗研究进展[J]. 内大学学报蒙古医科, 2024, 46(5): 520-557.
[18]  张国惠, 王欣钰. 特应性皮炎治疗的新进展[J]. 皮肤性病诊疗学杂志, 2024, 31(9): 643-651.

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