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Nursing Science 2025
重复经颅磁刺激治疗甲亢焦虑患者的临床疗效分析
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Abstract:
目的：分析重复经颅磁刺激治疗甲亢焦虑的临床疗效。方法：选取2024年6月至2024年12月贵阳市某三甲医院收治的甲亢焦虑患者58例作为研究对象，按照随机数字表法分为对照组和观察组，每组29例。采用焦虑自评量表(SAS)比较2组患者治疗前后焦虑状态的改善效果。结果：干预4周后，观察组的有效率显著高于对照组；观察组SAS评分显著低于对照组，差异均有统计学意义(P < 0.05)。结论：在药物治疗的基础上应用rTMs治疗甲亢焦虑患者，能缓解患者焦虑症状，治疗有效率较高，并且不良反应较少，值得今后在临床中使用。
Objective: To analyze the clinical efficacy of repetitive transcranial magnetic stimulation (rTMS) in the treatment of anxiety associated with hyperthyroidism. Methods: A total of 58 patients with hyperthyroidism-related anxiety admitted to a tertiary hospital in Guiyang City from June 2024 to December 2024 were selected as research subjects. They were randomly divided into a control group and an observation group, with 29 cases in each group. The Self-Rating Anxiety Scale (SAS) was used to compare the improvement of anxiety status between the two groups before and after treatment. Results: After 4 weeks of intervention, the effective rate of the observation group was significantly higher than that of the control group; the SAS score of the observation group was significantly lower than that of the control group, and the differences were statistically significant (P < 0.05). Conclusion: The application of rTMS in the treatment of hyperthyroidism-related anxiety on the basis of drug therapy can alleviate patients’ anxiety symptoms, with a high effective rate and fewer adverse reactions, making it worthy of use in future clinical practice.
| [1] | 中华医学会, 中华医学会杂志社, 中华医学会全科医学分会, 等. 甲状腺功能亢进症基层诊疗指南(2019年) [J]. 中华全科医师杂志, 2019, 18(12): 1118-1128. |
| [2] | Kahaly, G.J., Bartalena, L., Hegedüs, L., Leenhardt, L., Poppe, K. and Pearce, S.H. (2018) 2018 European Thyroid Association Guideline for the Management of Graves’ Hyperthyroidism. European Thyroid Journal, 7, 167-186. https://doi.org/10.1159/000490384 |
| [3] | 葛均波, 徐永健, 王辰. 内科学[M]. 北京: 人民卫生出版社, 2018. |
| [4] | 殷玉姣, 孙倩, 韩晶, 等. 甲状腺功能亢进患者的焦虑、抑郁情绪及相关因素分析[J]. 现代医学, 2022, 50(12): 1507-1511. |
| [5] | Huang, Y., Wang, Y., Wang, H., Liu, Z., Yu, X., Yan, J., et al. (2019) Prevalence of Mental Disorders in China: A Cross-Sectional Epidemiological Study. Lancet Psychiatry, 6, 211-224. https://doi.org/10.1016/s2215-0366(18)30511-x |
| [6] | 李江涛, 郑敏军, 曹辉. 经颅磁刺激技术的研究进展[J]. 高电压技术, 2016, 42(4): 1168-1178. |
| [7] | 冉胜兰, 邱康雨. 重复经颅磁刺激联合奥氮平治疗难治性精神分裂症患者的临床疗效[J]. 成都医学院学报, 2020, 15(2): 256-259. |
| [8] | 郝伟, 陆林. 精神病学[M]. 北京: 人民卫生出版社, 2018. |
| [9] | 倪青. 甲状腺功能亢进症病证结合诊疗指南(2021-01-20) [J]. 世界中医药, 2021, 16(2): 193-196. |
| [10] | 王文菁, 许明智. 焦虑自评量表在精神疾病患者中的因子结构研究[J]. 广东医学, 2009, 30(10): 1416-1418. |
| [11] | 姜丹. 综合护理干预对甲亢患者生活质量及焦虑抑郁情绪的影响[J]. 中国医药指南, 2023, 21(10): 162-164. |
| [12] | 杨珊, 王恺, 彭斌, 等. 黄连温胆汤加减联合经颅磁刺激治疗对广泛性焦虑症伴失眠患者HAMA、HAMD、PSQI评分及血清神经递质的影响[J]. 中国医学创新, 2023, 20(14): 67-71. |
| [13] | 马福兴, 孔传祥, 张红霞, 等. 分析右佐匹克隆联合重复经颅磁刺激对脑卒中后焦虑症伴睡眠障碍患者心理状态及睡眠质量的影响[J]. 世界睡眠医学杂志, 2024, 11(4): 717-720. |
| [14] | 刘飞, 张明园, 张晨, 等. rTMS仪联合艾司西酞普兰对门诊焦虑障碍患者焦虑症状、睡眠质量及认知功能的疗效研究[J]. 国际精神病学杂志, 2024, 51(3): 837-840, 851. |
| [15] | 张志文, 赵振丽. 重复经颅磁刺激联合帕罗西汀治疗广泛性焦虑症伴失眠患者的临床疗效[J]. 临床心身疾病杂志, 2024, 30(6): 6-10. |
| [16] | 陈莲, 付庆华. 高频重复经颅磁刺激治疗卒中后睡眠障碍的效果及对患者睡眠质量血清脑源性神经营养因子水平的影响[J]. 山西医药杂志, 2021, 50(6): 981-984. |
