Introduction: Atrial fibrillation (AF) and heart failure (HF) are two closely related cardiovascular diseases, whose association worsens prognosis and is a major public health concern. The aim of this study was to assess the prevalence of AF in patients with chronic heart failure at the cardiology department of CHU Ignace Deen. Methods: This was a cross-sectional, descriptive study conducted over a 7-month period, from April 1 to November 30, 2024, of patients hospitalized for IC associated with AF. Results: Out of 377 admissions, 31 cases of IC associated with AF were identified, representing a hospital prevalence of 8.22%. The majority of patients were men (70.96%; sex ratio: 2.4), with an average age of 58.8 ± 12.4 years. The age groups most affected were 51 - 60 years (41%) and 71 - 80 years (22.5%). The main risk factors included arterial hypertension (48.38%), diabetes (22.58%) and smoking (16.22%). The most frequent etiologies of AF-associated CI were coronary artery disease (48.38%), hypertension (25.89%) and valvular heart disease (9.67%). CHA2DS2-VASc score ≥ 3 was present in 38.70% of patients. Direct oral anticoagulants (DACs) were the most widely used antithrombotic therapy (64.51%), while beta-blockers were the most prescribed antiarrhythmic drugs (58.06%), followed by digoxin (32.25%). Conclusion: The increase in coronary artery disease and hypertension in Africa is helping to make atrial fibrillation a frequent cardiac rhythm disorder in hospitals.
References
[1]
Camm, A.J., Kirchhof, P., Lip, G.Y.H., Schotten, U., Savelieva, I., Ernst, S., et al. (2010) Guidelines for the Management of Atrial Fibrillation: The Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC). European Heart Journal, 31, 2369-2429. https://doi.org/10.1093/eurheartj/ehq278
[2]
Ragbaoui, Y., Chehbouni, C., Hammiri, A.E. and Habbal, R. (2017) Epidémiologie de l’association fibrillation atriale et insuffisance cardiaque. Pan African Medical Journal, 26, Article 116. https://doi.org/10.11604/pamj.2017.26.116.11470
[3]
Deedwania, P.C. and Lardizabal, J.A. (2010) Atrial Fibrillation in Heart Failure: A Comprehensive Review. The American Journal of Medicine, 123, 198-204. https://doi.org/10.1016/j.amjmed.2009.06.033
[4]
Lip, G.Y.H. (2012) Can We Predict Stroke in Atrial Fibrillation? Clinical Cardiology, 35, S21-S27. https://doi.org/10.1002/clc.20969
[5]
Colilla, S., Crow, A., Petkun, W., Singer, D.E., Simon, T. and Liu, X. (2013) Estimates of Current and Future Incidence and Prevalence of Atrial Fibrillation in the U.S. Adult Population. The American Journal of Cardiology, 112, 1142-1147. https://doi.org/10.1016/j.amjcard.2013.05.063
[6]
Gersh, B.J., Tsang, T.S.M., Barnes, M.E. and Seward, J.B. (2005) The Changing Epidemiology of Non-Valvular Atrial Fibrillation: The Role of Novel Risk Factors. European Heart Journal Supplements, 7, C5-C11. https://doi.org/10.1093/eurheartj/sui014
[7]
Songono, A., Kodio, A., Cissoko, A.S. et al. (2024) Epidemioclinical and Therapeutic Aspects of Atrial Fibrillation in Ségou (Mali): Clinical Presentation and Management of Atrial Fibrillation in Ségou (Mali). Health Sciences and Disease, 25, 51-55.
[8]
Charlemagne, A., Blacher, J., Cohen, A., Collet, J., Diévart, F., de Groote, P., et al. (2011) Epidemiology of Atrial Fibrillation in France: Extrapolation of International Epidemiological Data to France and Analysis of French Hospitalization Data. Archives of Cardiovascular Diseases, 104, 115-124. https://doi.org/10.1016/j.acvd.2010.11.012
[9]
Ellenga Mbolla, B.F., Gombet, T., Ikama, M.S., Dilou Bassemouka, L., Ekoba, J., Kimbally-Kaky, G., Nkoua, J.L. and Bouramoue, C. (2024) Fibrillation Auriculaire a Propos de 131 Cas Congolais. Médecined’Afrique Noire, 53, 73-78.
[10]
Gierula, J., Paton, M.F., Byrom, R., Cubbon, R.M., Kearney, M.T. and Witte, K.K. (2016) Reply. Journal of the American College of Cardiology, 68, 1253. https://doi.org/10.1016/j.jacc.2016.06.038
[11]
Mariko, S., Konaté, M., Sidibé, S., Traoré, K., Dollo, I., Traoré, F., Tolo, N., Diallo, N., Thiam, C.A., Sako, M., Kodio, A., Diakité, M., Sacko, A..K, Coulibaly, S., Diall, I.B., Menta, I. and Guindo, A. (2021) Epidemiology of the Atrial Fibrillation and Heart Failure Association at the Guindo Polyclinic in Bamako. Health Sciences and Disease, 22, 85-89.
[12]
Da Costa, A., Roméyer-Bouchard, C., Bisch, L., Khris, L. and Isaaz, K. (2009) Fibrillation atriale: Enjeux épidémiologiques, définition, nosologie, médico-économie. Annales de Cardiologie et d’Angéiologie, 58, S3-S5. https://doi.org/10.1016/s0003-3928(09)73388-8
[13]
Rich, M.W. (2009) Epidemiology of Atrial Fibrillation. Journal of Interventional Cardiac Electrophysiology, 25, 3-8. https://doi.org/10.1007/s10840-008-9337-8
[14]
Stewart, S., Wilkinson, D., Hansen, C., Vaghela, V., Mvungi, R., McMurray, J., et al. (2008) Predominance of Heart Failure in the Heart of Soweto Study Cohort: Emerging Challenges for Urban African Communities. Circulation, 118, 2360-2367. https://doi.org/10.1161/circulationaha.108.786244
[15]
Thiam, M. (2003) [Cardiac Insufficiency in the African Cardiology Milieu]. Bulletin de la Societe de PathologieExotique, 96, 217-218.
[16]
Guédon-Moreau, L. and Kacet, S. (2009) [Atrial Fibrillation: Challenge of Antithrombotic Treatment]. Annales de Cardiologie et d’Angéiologie, 58, S25-S30. https://doi.org/10.1016/s0003-3928(09)73395-5
[17]
Kotecha, D. and Piccini, J.P. (2015) Atrial Fibrillation in Heart Failure: What Should We Do? European Heart Journal, 36, 3250-3257. https://doi.org/10.1093/eurheartj/ehv513
