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呼吸机相关性肺损伤的研究进展与防治策略
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Abstract:
应用呼吸机进行机械通气是临床上治疗急性肺损伤、急性呼吸窘迫综合征及低氧血症的关键手段。然而，不当的参数设置常导致呼吸机相关性肺损伤，包括原发肺组织病变加重和健康肺泡受损，其高发生率和致死率已引起全球医学界的高度重视。本文就呼吸机相关性肺损伤的可能原因及当前临床认可的干预措施进行综述，特别强调了围术期精准肺保护策略的应用。
The use of ventilators for mechanical ventilation is a key clinical treatment for acute lung injury, acute respiratory distress syndrome and hypoxemia. However, improper parameter settings often lead to ventilator-associated lung injury, including exacerbation of primary lung tissue lesions and damage to healthy alveoli, and its high incidence and mortality have attracted the attention of the global medical community. This article reviews the possible causes of ventilator-associated lung injury and currently clinically accepted interventions, with particular emphasis on the application of perioperative precision lung protection strategies.
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