痛风与骨质疏松的相关性研究进展
Research Progress on the Correlation between Gout and Osteoporosis

近年来，由于经济的快速发展和生活水平的显著提高，患有痛风和骨质疏松症的患者明显增加，且两者同时出现的患病率也逐年增加，也成为了当前研究的热点问题。慢性高尿酸血症及尿酸盐结晶沉积的这种慢性疾病，不仅可能导致痛风，而且还可能引起肥胖、血管疾病、肾结石以及骨质疏松症的症状。痛风是指可能会在短时间内出现剧烈的疼痛和皮肤红肿，也可能会造成严重的关节损伤和疼痛。而骨质疏松症是一种全身性骨骼疾病，其特征是骨密度降低和骨组织微结构的破坏。对现有文献进行回顾分析显示，大量研究表明血清尿酸在调节骨代谢方面具有双重作用。
In recent years, due to the rapid development of economy and the significant improvement of living standards, the number of patients suffering from gout and osteoporosis has increased significantly, and the prevalence of both has also increased year by year, which has also become a hot issue in current research. Chronic hyperuricemia and the accumulation of urate crystals in this chronic disease may lead not only to gout, but also to symptoms of obesity, vascular disease, kidney stones, and osteoporosis. Gout refers to severe pain and swelling of the skin that may occur in a short period of time, and can also cause serious joint damage and pain. Osteoporosis, on the other hand, is a systemic bone disease characterized by decreased bone density and destruction of the microstructure of bone tissue. A review of existing literature shows that a large number of studies have shown that serum uric acid has a dual role in regulating bone metabolism.