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新生儿色素失禁症1例并文献复习
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Abstract:
患儿，女，10余天。因出生后全身皮疹10余天就诊。体格检查：躯干可见散在红斑，其上可见水疱。四肢可见呈线状分布红斑，其上可见水疱、脓疱及黄痂、鳞屑。组织病理示：表层皮肤组织表皮角化不全，棘层细胞松解，角质层及表皮内见较多嗜酸性粒细胞浸润，基底层液化变形，上皮角向下延伸，真皮层小血管周见较多炎性细胞水(含淋巴细胞及嗜酸性粒细胞)浸润，符合色素失禁症。诊断：新生儿色素失禁症。
Patient, female, 10 days old, she was taken to the hospital 10 days after birth due to a rash all over her body. Physical examination: Scattered red spots were visible on the torso, and blisters were visible on them. Red spots in a linear distribution were visible on the limbs, and blisters, pustules, yellow scabs and scales were visible on them. Histopathology showed that epidermal keratinization was incomplete in the superficial skin tissue, the cells in the spinous layer were loose, there was a relatively large number of eosinophilic granulomas in the stratum corneum and within the epidermis, the basal layer was liquefied and deformed, the epithelial corners extended downward, and there was a relatively large number of inflammatory cells (including lymphocytes and eosinophils) surrounding the small blood vessels in the dermis. Diagnosis: neonatal ichthyosis.
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